eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

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Synonym

EIF-2, EIF-2alpha, EIF-2A, eIF-2-alpha, EIF2S1, EIF2A

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:81.80

cerebellum:88.20

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:61.30

spine:-

retina:237.30

eye:70.50

artery/aorta:60

vein:-

lymphnode:202.20

peripheral blood:36.40

spleen:56.70

thymus:77.30

bone marrow:39.40

adipose:201.70

bone:102.40

skin:211.20

GeneChip

cerebrum:7.16

cerebellum:7.32

brain stem:7.21

corpus callosum/glia:7.13

pineal gland:-

peripheral nerve:7.39

spine:7.17

retina:-

eye:-

artery/aorta:7.56

vein:7.86

lymphnode:7.56

peripheral blood:-

spleen:7.35

thymus:7.84

bone marrow:7.53

adipose:7.57

bone:-

skin:7.66

CAGE

cerebrum:3.94

cerebellum:-

brain stem:3.98

corpus callosum/glia:3.69

pineal gland:3.89

peripheral nerve:-

spine:3.88

retina:-

eye:-

artery/aorta:3.68

vein:3.61

lymphnode:3.74

peripheral blood:-

spleen:3.96

thymus:3.98

bone marrow:-

adipose:4.46

bone:-

skin:-

RNA-seq

cerebrum:4.24

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.94

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.56

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:127.50

prostate:90.10

ovary:111.80

testis:116.80

heart:51.10

muscle:40.20

esophagus:-

stomach:85

intestine:32.40

colon:67.80

liver/hepato:63.30

lung:122.20

bladder:125.60

kidney:124.80

pituitary:232

thyroid/parathyroid:-

adrenal gland:-

pancreas:71.10

breast:195.20

salivary:-

GeneChip

uterus:7.58

placenta:7.74

prostate:7.82

ovary:7.57

testis:8.17

heart:7.78

muscle:7.97

esophagus:8.01

stomach:7.46

intestine:7.67

colon:7.38

liver/hepato:7.35

lung:7.58

bladder:-

kidney:7.34

pituitary:6.67

thyroid/parathyroid:7.35

adrenal gland:7.62

pancreas:8.10

breast:7.50

salivary:7.36

CAGE

uterus:3.90

placenta:4.09

prostate:4.12

ovary:3.98

testis:4.38

heart:4.15

muscle:4.44

esophagus:4.29

stomach:-

intestine:3.75

colon:3.65

liver/hepato:4.48

lung:3.61

bladder:4.29

kidney:3.98

pituitary:3.74

thyroid/parathyroid:4.14

adrenal gland:-

pancreas:4.06

breast:3.75

salivary:3.84

RNA-seq

uterus:-

placenta:-

prostate:4.57

ovary:4.32

testis:4.94

heart:4.10

muscle:4.65

esophagus:-

stomach:-

intestine:-

colon:4.90

liver/hepato:4.04

lung:4.21

bladder:-

kidney:4.11

pituitary:-

thyroid/parathyroid:4.58

adrenal gland:4.07

pancreas:-

breast:4.45

salivary:-

IDs

Refseq ID	NM_004094
Gene ID	1965
Unigene ID	Hs.151777
Probe set ID	201144_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134001
GTEx ID	ENSG00000134001

Orthologous Gene

Mouse[2]	NM_026114
Rat [0]

Chromosomal Region

14q23.3 [67,826,714 - 67,853,233]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR012340	Nucleic acid-binding, OB-fold
IPR016027	Nucleic acid-binding, OB-fold-like
IPR003029	Ribosomal protein S1, RNA binding domain

GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0044267	cellular protein metabolic process
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0010467	gene expression
GO:0046777	protein amino acid autophosphorylation
GO:0043558	regulation of translational initiation in response to stress
GO:0006412	translation
GO:0006413	translational initiation

GO:0005829	cytosol
GO:0005850	eukaryotic translation initiation factor 2 complex
GO:0005851	eukaryotic translation initiation factor 2B complex
GO:0005634	nucleus
GO:0005844	polysome
GO:0010494	stress granule

GO:0005515	protein binding
GO:0043022	ribosome binding
GO:0003743	translation initiation factor activity

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function