adenylate cyclase 4

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Synonym

Adenylyl cyclase 4, ADCY4, Adenylate cyclase type 4, adenylate cyclase 4, Adenylate cyclase type IV, ATP pyrophosphate-lyase 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:11.80 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:37.80 thymus:25.80 bone marrow:39.40 adipose:80.70 bone:25.60 skin:4.80
GeneChip nodata
CAGE cerebrum:1.49 cerebellum:- brain stem:1.56 corpus callosum/glia:1.41 pineal gland:1.38 peripheral nerve:- spine:1.69 retina:- eye:- artery/aorta:2.26 vein:3.10 lymphnode:2.23 peripheral blood:- spleen:2.69 thymus:0.61 bone marrow:- adipose:3.21 bone:- skin:-
RNA-seq cerebrum:0.43 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.52 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.70 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:72.90 prostate:45.10 ovary:- testis:38.90 heart:114.90 muscle:- esophagus:- stomach:- intestine:- colon:42.40     liver/hepato:10.60        lung:19.60    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:3.25 placenta:2.90 prostate:2.23 ovary:1.80 testis:1.46 heart:3.23 muscle:2.31 esophagus:2.34 stomach:- intestine:1.53 colon:2.09     liver/hepato:1.41    lung:2.91 bladder:2.02 kidney:1.97 pituitary:0.95 thyroid/parathyroid:2.04 adrenal gland:- pancreas:1.59 breast:2.79 salivary:1.00
RNA-seq uterus:- placenta:- prostate:1.82 ovary:0.38 testis:1.09 heart:1.03 muscle:0.88 esophagus:- stomach:- intestine:- colon:0.93     liver/hepato:0.10        lung:0.84    bladder:- kidney:1.40 pituitary:- thyroid/parathyroid:1.17 adrenal gland:2.68 pancreas:- breast:2.25 salivary:-

Gene Information

IDs

Refseq ID NM_139247
Gene ID 196883
Unigene ID Hs.443428
Probe set ID -
Ensembl ID ENSG00000129467
GTEx ID ENSG00000129467

Orthologous Gene

Mouse[1]  NM_080435
Rat [0]  

Chromosomal Region

14q12  [24,787,555  -  24,804,277]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2165385
7766992
7959689
8663304
9417641
10089566
10807185
10808179
11055432
11299302
11549699
11884542
12477932
12503609
12626323
14702039
14993377
15489334
17081159
21228062
21890473
22505724

Gene Ontology  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007202  activation of phospholipase C activity
GO:0034199  activation of protein kinase A activity
GO:0006171  cAMP biosynthetic process
GO:0071377  cellular response to glucagon stimulus
GO:0006112  energy reserve metabolic process
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007188  G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0045087  innate immune response
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007165  signal transduction
GO:0007268  synaptic transmission
GO:0055085  transmembrane transport
GO:0006833  water transport

Cellular Component

GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004016  adenylate cyclase activity
GO:0005524  ATP binding
GO:0046872  metal ion binding
GO:0005515  protein binding