eukaryotic translation initiation factor 4A, isoform 1

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Synonym

EIF4A1, ATP-dependent RNA helicase eIF4A-1, eIF-4A-I, EIF-4A, Eukaryotic initiation factor 4A-I, EIF4A, DDX2A, eIF4A-I

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:591.40

cerebellum:478.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:296.70

peripheral nerve:276

spine:561.50

retina:355.90

eye:523.10

artery/aorta:1049.10

vein:1199.70

lymphnode:586.40

peripheral blood:7560.70

spleen:1039.90

thymus:592.70

bone marrow:492

adipose:927.70

bone:1087.60

skin:331.20

GeneChip

cerebrum:9.27

cerebellum:8.95

brain stem:9.25

corpus callosum/glia:9.35

pineal gland:-

peripheral nerve:9.98

spine:9.51

retina:-

eye:-

artery/aorta:10.49

vein:10.30

lymphnode:10.29

peripheral blood:-

spleen:10.05

thymus:10.53

bone marrow:10.37

adipose:10.45

bone:-

skin:10.64

CAGE

cerebrum:2.62

cerebellum:-

brain stem:2.87

corpus callosum/glia:3.06

pineal gland:2.47

peripheral nerve:-

spine:3.30

retina:-

eye:-

artery/aorta:3.42

vein:3.28

lymphnode:3.88

peripheral blood:-

spleen:3.59

thymus:4.03

bone marrow:-

adipose:3.67

bone:-

skin:-

RNA-seq

cerebrum:3.45

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.92

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.24

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:410.10

placenta:746.80

prostate:214

ovary:596.20

testis:510.50

heart:510.90

muscle:200.90

esophagus:1028.50

stomach:594.80

intestine:842.40

colon:508.80

liver/hepato:443.30

lung:542.50

bladder:125.60

kidney:363.90

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:711

pancreas:577.90

breast:399.60

salivary:-

GeneChip

uterus:10.37

placenta:10

prostate:10.40

ovary:10.66

testis:10.43

heart:9.65

muscle:8.61

esophagus:10.97

stomach:10.12

intestine:10

colon:10.35

liver/hepato:9.85

lung:10.48

bladder:-

kidney:9.68

pituitary:9.94

thyroid/parathyroid:9.39

adrenal gland:10.61

pancreas:10.48

breast:10.52

salivary:9.55

CAGE

uterus:3.50

placenta:3.34

prostate:3.22

ovary:3.69

testis:3.11

heart:2.86

muscle:2.80

esophagus:3.75

stomach:-

intestine:3.12

colon:3.23

liver/hepato:3.67

lung:3.26

bladder:3.52

kidney:3.25

pituitary:3.13

thyroid/parathyroid:3.14

adrenal gland:-

pancreas:3.77

breast:3.49

salivary:4.04

RNA-seq

uterus:-

placenta:-

prostate:4.92

ovary:6.00

testis:5.37

heart:3.16

muscle:3.97

esophagus:-

stomach:-

intestine:-

colon:5.67

liver/hepato:4.98

lung:6.45

bladder:-

kidney:5.10

pituitary:-

thyroid/parathyroid:4.60

adrenal gland:5.46

pancreas:-

breast:5.33

salivary:-

IDs

Refseq ID	NM_001416
Gene ID	1973
Unigene ID	Hs.129673
Probe set ID	201530_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000161960
GTEx ID	ENSG00000161960

Orthologous Gene

Mouse[18]	NM_001159375, NM_144958
Rat[1]	NM_199372, NM_144958

Chromosomal Region

17p13.1 [7,476,024 - 7,482,324]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR014001	DEAD-like helicase, N-terminal
IPR014021	Helicase, superfamily 1/2, ATP-binding domain

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0044267	cellular protein metabolic process
GO:0019221	cytokine-mediated signaling pathway
GO:0010467	gene expression
GO:0016071	mRNA metabolic process
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0016070	RNA metabolic process
GO:0006412	translation
GO:0006413	translational initiation
GO:0019048	virus-host interaction

Cellular Component

GO:0005829	cytosol
GO:0016281	eukaryotic translation initiation factor 4F complex

Molecular Function

GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0004386	helicase activity
GO:0003729	mRNA binding
GO:0005515	protein binding
GO:0000339	RNA cap binding
GO:0008135	translation factor activity, nucleic acid binding
GO:0003743	translation initiation factor activity

eukaryotic translation initiation factor 4A, isoform 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function