essential meiotic endonuclease 1 homolog 2 (S. pombe)

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Synonym

FLJ00151, gs125, EME2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:23.50 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:4.80
GeneChip nodata
CAGE cerebrum:0.18 cerebellum:- brain stem:0.15 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.47 vein:0.34 lymphnode:0.22 peripheral blood:- spleen:0 thymus:0.28 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.39 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:37.30 testis:13 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:- salivary:-
GeneChip nodata
CAGE uterus:0.07 placenta:0.08 prostate:0 ovary:0 testis:0.04 heart:0 muscle:0 esophagus:0.68 stomach:- intestine:0.21 colon:0.35     liver/hepato:0    lung:0 bladder:0 kidney:0.15 pituitary:0.50 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.33 ovary:0.25 testis:0.24 heart:0.20 muscle:0 esophagus:- stomach:- intestine:- colon:0.11     liver/hepato:0.05        lung:0.22    bladder:- kidney:0.31 pituitary:- thyroid/parathyroid:0.64 adrenal gland:0.98 pancreas:- breast:0.29 salivary:-

Gene Information

IDs

Refseq ID NM_001010865
Gene ID 197342
Unigene ID Hs.7247
Probe set ID -
Ensembl ID ENSG00000197774
GTEx ID ENSG00000197774

Orthologous Gene

Mouse[1]  NM_001163102
Rat[1]  NM_001163102

Chromosomal Region

16p13.3  [1,823,229  -  1,826,239]

Gene Family (Interpro ID)

IPR006166  ERCC4 domain
IPR011335  Restriction endonuclease, type II-like, core

Link to Pubmed  (Pubmed ID)

11157797
12477932
12721304
17289582
24371268
24692662

Gene Ontology  (GO ID)

Biological Process

GO:0006310  DNA recombination
GO:0006281  DNA repair

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0004519  endonuclease activity