eukaryotic translation initiation factor 4 gamma, 1

Synonym

EIF4GI, EIF4G, Eukaryotic translation initiation factor 4 gamma 1, eIF-4G1, EIF4G1, eIF-4G 1, eIF-4-gamma 1, p220, DKFZp686A1451

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:112.60

cerebellum:63

brain stem:-

corpus callosum/glia:116.60

pineal gland:-

peripheral nerve:30.70

spine:561.50

retina:-

eye:352.60

artery/aorta:179.90

vein:266.60

lymphnode:202.20

peripheral blood:109.30

spleen:132.30

thymus:128.80

bone marrow:295.20

adipose:363

bone:358.30

skin:268.80

GeneChip

cerebrum:7.49

cerebellum:7.74

brain stem:7.46

corpus callosum/glia:7.65

pineal gland:-

peripheral nerve:7.99

spine:7.71

retina:-

eye:-

artery/aorta:8.06

vein:8.20

lymphnode:8.16

peripheral blood:-

spleen:7.83

thymus:7.77

bone marrow:8.07

adipose:8.27

bone:-

skin:8.54

CAGE

cerebrum:4.41

cerebellum:-

brain stem:4.46

corpus callosum/glia:4.50

pineal gland:4.22

peripheral nerve:-

spine:4.38

retina:-

eye:-

artery/aorta:4.69

vein:4.80

lymphnode:4.78

peripheral blood:-

spleen:4.99

thymus:4.58

bone marrow:-

adipose:4.83

bone:-

skin:-

RNA-seq

cerebrum:2.52

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.53

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.56

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:182.30

placenta:196.70

prostate:236.60

ovary:74.50

testis:220.60

heart:76.60

muscle:200.90

esophagus:-

stomach:148.70

intestine:-

colon:407

liver/hepato:31.70

lung:263.90

bladder:251.20

kidney:114.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:53.30

breast:1143

salivary:-

GeneChip

uterus:8.05

placenta:8.40

prostate:8.32

ovary:8.24

testis:8.45

heart:8.12

muscle:8.82

esophagus:9.30

stomach:8.24

intestine:8.25

colon:8.26

liver/hepato:8.78

lung:8.43

bladder:-

kidney:8.07

pituitary:7.82

thyroid/parathyroid:8.31

adrenal gland:8.41

pancreas:8.10

breast:8.45

salivary:8.39

CAGE

uterus:4.61

placenta:4.97

prostate:4.64

ovary:4.88

testis:4.94

heart:4.92

muscle:5.69

esophagus:5.31

stomach:-

intestine:4.93

colon:4.55

liver/hepato:6.01

lung:4.93

bladder:4.86

kidney:5.16

pituitary:4.69

thyroid/parathyroid:4.84

adrenal gland:-

pancreas:5.23

breast:4.96

salivary:4.90

RNA-seq

uterus:-

placenta:-

prostate:2.05

ovary:2.33

testis:3.93

heart:1.25

muscle:4.69

esophagus:-

stomach:-

intestine:-

colon:1.38

liver/hepato:3.73

lung:2.15

bladder:-

kidney:4.19

pituitary:-

thyroid/parathyroid:2.18

adrenal gland:3.35

pancreas:-

breast:2.28

salivary:-

IDs

Refseq ID	NM_004953
Gene ID	1981
Unigene ID	Hs.433750
Probe set ID	208625_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000114867
GTEx ID	ENSG00000114867

Orthologous Gene

Mouse[6]	NM_001005331, NM_145941
Rat[6]	NM_001005331, NM_145941

Chromosomal Region

3q27.1 [184,032,283 - 184,053,146]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016024	Armadillo-type fold
IPR003307	eIF4-gamma/eIF5/eIF2-epsilon

Gene Ontology (GO ID)

Biological Process

GO:0008219	cell death
GO:0044267	cellular protein metabolic process
GO:0019221	cytokine-mediated signaling pathway
GO:0010467	gene expression
GO:0008286	insulin receptor signaling pathway
GO:0016071	mRNA metabolic process
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
GO:0006446	regulation of translational initiation
GO:0016070	RNA metabolic process
GO:0006412	translation
GO:0006413	translational initiation
GO:0019048	virus-host interaction

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016281	eukaryotic translation initiation factor 4F complex

Molecular Function

GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008135	translation factor activity, nucleic acid binding
GO:0003743	translation initiation factor activity

eukaryotic translation initiation factor 4 gamma, 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function