eukaryotic translation initiation factor 4 gamma, 2

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Synonym

Eukaryotic translation initiation factor 4 gamma 2, DAP5, AAG1, OK/SW-cl.75, Death-associated protein 5, eIF4G 2, DAP-5, eIF-4-gamma 2, EIF4G2, FLJ41344, eIF-4G 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1418.60 cerebellum:1826.10 brain stem:- corpus callosum/glia:874.80 pineal gland:- peripheral nerve:1441.60 spine:1123 retina:237.30 eye:352.60 artery/aorta:5065.80 vein:333.20 lymphnode:364 peripheral blood:382.60 spleen:699.50 thymus:1417.20 bone marrow:531.40 adipose:403.30 bone:793.30 skin:537.60
GeneChip cerebrum:10.06 cerebellum:9.73 brain stem:10.36 corpus callosum/glia:10.03 pineal gland:- peripheral nerve:10.42 spine:10.41 retina:- eye:- artery/aorta:10.24 vein:10.13 lymphnode:10.26 peripheral blood:- spleen:10.37 thymus:11.09 bone marrow:9.80 adipose:10.30 bone:- skin:10.63
CAGE cerebrum:6.76 cerebellum:- brain stem:6.79 corpus callosum/glia:6.71 pineal gland:7.30 peripheral nerve:- spine:7.45 retina:- eye:- artery/aorta:7.01 vein:6.88 lymphnode:6.85 peripheral blood:- spleen:7.28 thymus:7.05 bone marrow:- adipose:6.97 bone:- skin:-
RNA-seq cerebrum:4.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.37 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:1941.10 placenta:666.70 prostate:225.30 ovary:894.30 testis:1393.10 heart:459.80 muscle:642.90 esophagus:342.80 stomach:722.20 intestine:615.60 colon:415.50     liver/hepato:337.80        lung:1593.30    bladder:502.40 kidney:187.10 pituitary:579.90 thyroid/parathyroid:491.20 adrenal gland:507.90 pancreas:613.50 breast:966.50 salivary:328.40
GeneChip uterus:10.70 placenta:10.66 prostate:10.95 ovary:10.58 testis:10.52 heart:10.19 muscle:10.43 esophagus:10.44 stomach:10.13 intestine:10.12 colon:9.80 liver/hepato:9.54 lung:10.42 bladder:- kidney:10.09 pituitary:10.36 thyroid/parathyroid:10.53 adrenal gland:10.21 pancreas:9.57 breast:10.24 salivary:9.92
CAGE uterus:7.19 placenta:7.67 prostate:7.10 ovary:6.89 testis:6.88 heart:7.36 muscle:7.54 esophagus:7.35 stomach:- intestine:7.12 colon:6.94     liver/hepato:7.10    lung:7.17 bladder:7.22 kidney:7.27 pituitary:7.26 thyroid/parathyroid:7.14 adrenal gland:- pancreas:6.78 breast:7.40 salivary:6.96
RNA-seq uterus:- placenta:- prostate:4.68 ovary:5.10 testis:4.56 heart:4.09 muscle:3.14 esophagus:- stomach:- intestine:- colon:4.99     liver/hepato:5.13        lung:5.47    bladder:- kidney:5.22 pituitary:- thyroid/parathyroid:5.60 adrenal gland:5.53 pancreas:- breast:5.76 salivary:-

Gene Information

IDs

Refseq ID NM_001042559
Gene ID 1982
Unigene ID Hs.183684
Probe set ID 200004_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000110321
GTEx ID ENSG00000110321

Orthologous Gene

Mouse[8]  NM_001040131, NM_013507
Rat[1]  NM_001017374, NM_013507

Chromosomal Region

11p15.3  [10,818,597  -  10,830,657]

Gene Family (Interpro ID)

IPR016024  Armadillo-type fold
IPR003307  eIF4-gamma/eIF5/eIF2-epsilon

Link to Pubmed  (Pubmed ID)

8125298
9027506
9032289
9049310
9372926
9418880
9878069
10394359
10611228
11172724
11175261
11331597
11511540
11943866
12477932
12505164
12665801
12703993
14507913
14702039
15016848
15231748
15302935
15361857
15489334
15718103
16166382
16289705
16344560
16410684
16751776
16932749
17195095
17237356
17353931
18450493
18491231
18722383
19615732
19738201
19769989
19946888
20057060
20467438
20544972
21139048
21145461
21890473
21906983
21963094
21988832
22505724
22555068
22623428
22909319
22939629
23000965
23318444
24497838
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007050  cell cycle arrest
GO:0008219  cell death
GO:0019221  cytokine-mediated signaling pathway
GO:0006446  regulation of translational initiation
GO:0016070  RNA metabolic process

Cellular Component

GO:0005829  cytosol
GO:0016281  eukaryotic translation initiation factor 4F complex

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0008135  translation factor activity, nucleic acid binding
GO:0003743  translation initiation factor activity