allograft inflammatory factor 1

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Synonym

G1, Ionized calcium-binding adapter molecule 1, AIF-1, Protein G1, IRT-1, AIF1, Allograft inflammatory factor 1, IBA1, allograft inflammatory factor 1, Em:AF129756.17

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:89.90 vein:- lymphnode:495.40 peripheral blood:91.10 spleen:18.90 thymus:25.80 bone marrow:196.80 adipose:- bone:- skin:9.60
GeneChip cerebrum:7.24 cerebellum:6.67 brain stem:7.53 corpus callosum/glia:7.92 pineal gland:- peripheral nerve:7.62 spine:7.87 retina:- eye:- artery/aorta:7.36 vein:7.31 lymphnode:8.23 peripheral blood:- spleen:8.56 thymus:8.55 bone marrow:8.90 adipose:7.70 bone:- skin:7.12
CAGE cerebrum:3.41 cerebellum:- brain stem:4.21 corpus callosum/glia:4.53 pineal gland:2.66 peripheral nerve:- spine:4.48 retina:- eye:- artery/aorta:3.36 vein:4.47 lymphnode:4.62 peripheral blood:- spleen:6.23 thymus:5.74 bone marrow:- adipose:4.09 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:51 prostate:45.10 ovary:- testis:8.70 heart:191.60 muscle:60.30 esophagus:- stomach:21.20 intestine:- colon:-     liver/hepato:31.70        lung:34.20    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:8.90 breast:9.30 salivary:-
GeneChip uterus:7.03 placenta:7.63 prostate:6.88 ovary:7.11 testis:6.50 heart:7.34 muscle:6.74 esophagus:6.79 stomach:7.02 intestine:7.30 colon:7.15 liver/hepato:7.38 lung:8.18 bladder:- kidney:7.40 pituitary:7.06 thyroid/parathyroid:6.77 adrenal gland:7.37 pancreas:7.10 breast:7.13 salivary:7.04
CAGE uterus:3.03 placenta:4.43 prostate:3.61 ovary:3.38 testis:2.65 heart:3.12 muscle:2.70 esophagus:3.09 stomach:- intestine:4.06 colon:2.92     liver/hepato:4.05    lung:4.47 bladder:3.31 kidney:3.86 pituitary:2.89 thyroid/parathyroid:2.76 adrenal gland:- pancreas:2.86 breast:2.59 salivary:2.85
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001623
Gene ID 199
Unigene ID Hs.76364
Probe set ID 215051_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204472
ENSG00000206428
ENSG00000234836
ENSG00000235588
ENSG00000235985
ENSG00000237727
GTEx ID ENSG00000204472
ENSG00000206428
ENSG00000234836
ENSG00000235588
ENSG00000235985
ENSG00000237727

Orthologous Gene

Mouse[1]  NM_019467
Rat [0]  

Chromosomal Region

HSCHR6_MHC_COX  [31,570,375  -  31,572,212]
6p21.33  [31,582,961  -  31,584,798]
HSCHR6_MHC_SSTO  [31,572,910  -  31,574,747]
HSCHR6_MHC_QBL  [31,573,205  -  31,575,042]
HSCHR6_MHC_MCF  [31,659,258  -  31,661,095]
HSCHR6_MHC_DBB  [31,565,139  -  31,566,976]

Gene Family (Interpro ID)

IPR018249  EF-HAND 2

Link to Pubmed  (Pubmed ID)

7769138
8499947
8629302
8912632
9614071
10202016
11500035
11557666
11943136
12477932
12559634
12714565
12887599
14574404
14656967
14756805
15117732
15489334
15784173
15922740
16049345
16291819
16868985
17010532
17011575
17035944
17073733
17498268
17522098
17533487
17907195
18341653
18699778
18721278
18787073
18816612
18835879
18987644
19079260
19204726
19745784
19851445
20237496
20587610
20662065
20850992
20855536
21040744
21168672
21509525
21720444
21890473
22106834
22116621
22225958
22505724
22560794
22936669
23221708
23547889
23563607
23777936
23867161
24018427

Gene Ontology  (GO ID)

Biological Process

GO:0051017  actin filament bundle formation
GO:0030041  actin filament polymerization
GO:0071346  cellular response to interferon-gamma
GO:0006954  inflammatory response
GO:0001774  microglial cell activation
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0006911  phagocytosis, engulfment
GO:0090026  positive regulation of monocyte chemotaxis
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0042102  positive regulation of T cell proliferation
GO:0016601  Rac protein signal transduction

Cellular Component

GO:0005884  actin filament
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030027  lamellipodium
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0001891  phagocytic cup
GO:0032587  ruffle membrane

Molecular Function

GO:0051015  actin filament binding
GO:0005509  calcium ion binding
GO:0003674  molecular_function