epithelial membrane protein 2

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Synonym

MGC9056, Protein XMP, EMP2, EMP-2, epithelial membrane protein 2, XMP, Epithelial membrane protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:118.60 eye:64.60 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:37.80 thymus:- bone marrow:19.70 adipose:40.30 bone:76.80 skin:115.20
GeneChip cerebrum:5.25 cerebellum:4.87 brain stem:5.52 corpus callosum/glia:5.31 pineal gland:- peripheral nerve:7.60 spine:5.49 retina:- eye:- artery/aorta:7.90 vein:6.76 lymphnode:6.64 peripheral blood:- spleen:6.06 thymus:4.98 bone marrow:5.18 adipose:7.61 bone:- skin:8.63
CAGE cerebrum:1.68 cerebellum:- brain stem:1.99 corpus callosum/glia:1.94 pineal gland:1.82 peripheral nerve:- spine:2.20 retina:- eye:- artery/aorta:4.23 vein:2.77 lymphnode:3.04 peripheral blood:- spleen:2.32 thymus:1.35 bone marrow:- adipose:3.50 bone:- skin:-
RNA-seq cerebrum:2.98 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.40 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.71 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:87.40 prostate:78.90 ovary:37.30 testis:13 heart:281 muscle:20.10 esophagus:- stomach:106.20 intestine:32.40 colon:195     liver/hepato:116.10        lung:395.90    bladder:- kidney:- pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:167.30 salivary:328.40
GeneChip uterus:6.83 placenta:7.51 prostate:7.64 ovary:7.11 testis:5.66 heart:7.44 muscle:5.90 esophagus:8.70 stomach:7.12 intestine:6.48 colon:7.56 liver/hepato:6.60 lung:10.12 bladder:- kidney:5.64 pituitary:5.86 thyroid/parathyroid:6.40 adrenal gland:6.02 pancreas:6.25 breast:7.99 salivary:7.12
CAGE uterus:3.13 placenta:3.69 prostate:3.15 ovary:3.18 testis:2.08 heart:3.37 muscle:2.58 esophagus:4.14 stomach:- intestine:2.60 colon:3.13     liver/hepato:4.34    lung:5.66 bladder:2.97 kidney:1.84 pituitary:1.74 thyroid/parathyroid:2.60 adrenal gland:- pancreas:1.87 breast:4.03 salivary:2.63
RNA-seq uterus:- placenta:- prostate:4.70 ovary:5.46 testis:4.07 heart:4.46 muscle:3.04 esophagus:- stomach:- intestine:- colon:5.40     liver/hepato:4.82        lung:7.33    bladder:- kidney:3.27 pituitary:- thyroid/parathyroid:4.21 adrenal gland:4.46 pancreas:- breast:4.84 salivary:-

Gene Information

IDs

Refseq ID NM_001424
Gene ID 2013
Unigene ID Hs.531561
Probe set ID 204975_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000213853
GTEx ID ENSG00000213853

Orthologous Gene

Mouse[3]  NM_007929
Rat [0]  

Chromosomal Region

16p13.13  [10,622,279  -  10,674,555]

Gene Family (Interpro ID)

IPR003933  Epithelial membrane protein EMP-2
IPR004032  PMP-22/EMP/MP20
IPR004031  PMP-22/EMP/MP20/Claudin

Link to Pubmed  (Pubmed ID)

8884260
8917086
8996089
10331954
11713717
11752456
12477932
12710941
12782127
14702039
15489334
16216233
16341674
16344560
17544801
17609206
18400107
19010852
20670949
20732626
21637765
23319000
23334331
23568457
23838430

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion

Cellular Component

GO:0016324  apical plasma membrane
GO:0016021  integral to membrane

Molecular Function

GO:0005178  integrin binding