RAB12, member RAS oncogene family

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Synonym

FLJ45927, RAB12, RAB12, member RAS oncogene family, MGC104724

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:23.50 artery/aorta:- vein:- lymphnode:50.60 peripheral blood:18.20 spleen:18.90 thymus:25.80 bone marrow:- adipose:- bone:12.80 skin:19.20
GeneChip nodata
CAGE cerebrum:4.32 cerebellum:- brain stem:4.03 corpus callosum/glia:4.12 pineal gland:3.93 peripheral nerve:- spine:4.00 retina:- eye:- artery/aorta:4.40 vein:3.74 lymphnode:3.95 peripheral blood:- spleen:4.24 thymus:3.39 bone marrow:- adipose:4.34 bone:- skin:-
RNA-seq cerebrum:4.91 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.19 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:43.70 prostate:- ovary:- testis:21.60 heart:12.80 muscle:20.10 esophagus:- stomach:21.20 intestine:- colon:17     liver/hepato:31.70        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:80 breast:74.30 salivary:328.40
GeneChip nodata
CAGE uterus:4.40 placenta:4.24 prostate:4.26 ovary:4.20 testis:3.83 heart:4.76 muscle:5.10 esophagus:4.30 stomach:- intestine:3.66 colon:4.03     liver/hepato:4.16    lung:4.46 bladder:4.44 kidney:4.11 pituitary:4.12 thyroid/parathyroid:3.85 adrenal gland:- pancreas:2.94 breast:4.00 salivary:3.50
RNA-seq uterus:- placenta:- prostate:5.02 ovary:4.88 testis:4.37 heart:5.51 muscle:6.70 esophagus:- stomach:- intestine:- colon:5.14     liver/hepato:3.96        lung:5.43    bladder:- kidney:4.38 pituitary:- thyroid/parathyroid:4.97 adrenal gland:4.86 pancreas:- breast:4.86 salivary:-

Gene Information

IDs

Refseq ID NM_001025300
Gene ID 201475
Unigene ID Hs.270074
Probe set ID -
Ensembl ID ENSG00000206418
GTEx ID ENSG00000206418

Orthologous Gene

Mouse[1]  NM_024448
Rat[1]  NM_013017

Chromosomal Region

18p11.22  [8,609,443  -  8,639,380]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

12477932
15489334
20360680
21139048
21890473
22178446
23000965
23357852

Gene Ontology  (GO ID)

Biological Process

GO:0044257  cellular protein catabolic process
GO:0008333  endosome to lysosome transport
GO:0015031  protein transport
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0000139  Golgi membrane
GO:0005765  lysosomal membrane
GO:0005764  lysosome
GO:0055038  recycling endosome membrane

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding