erythrocyte membrane protein band 4.9 (dematin)

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Synonym

Erythrocyte membrane protein band 4.9, Dematin, EPB49, erythrocyte membrane protein band 4.9 (dematin), DMT, DEMATIN

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:250.10 cerebellum:226.70 brain stem:- corpus callosum/glia:204.10 pineal gland:- peripheral nerve:30.70 spine:449.20 retina:- eye:105.80 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:54.70 spleen:37.80 thymus:- bone marrow:39.40 adipose:40.30 bone:12.80 skin:4.80
GeneChip cerebrum:7.96 cerebellum:7.34 brain stem:7.55 corpus callosum/glia:6.46 pineal gland:- peripheral nerve:7.43 spine:7 retina:- eye:- artery/aorta:6.92 vein:6.66 lymphnode:6.45 peripheral blood:- spleen:6.32 thymus:5.92 bone marrow:8.71 adipose:7.03 bone:- skin:6.70
CAGE cerebrum:5.28 cerebellum:- brain stem:3.91 corpus callosum/glia:3.62 pineal gland:3.30 peripheral nerve:- spine:3.51 retina:- eye:- artery/aorta:3.59 vein:2.63 lymphnode:2.21 peripheral blood:- spleen:2.78 thymus:0.83 bone marrow:- adipose:3.48 bone:- skin:-
RNA-seq cerebrum:0.86 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.83 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:- ovary:74.50 testis:21.60 heart:- muscle:40.20 esophagus:- stomach:21.20 intestine:129.60 colon:-     liver/hepato:63.30        lung:14.70    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:53.30 breast:37.20 salivary:-
GeneChip uterus:6.27 placenta:6.27 prostate:6.63 ovary:6.37 testis:6.15 heart:6.93 muscle:6.84 esophagus:6.61 stomach:6.60 intestine:6.57 colon:6.71 liver/hepato:6.63 lung:6.65 bladder:- kidney:7.43 pituitary:8.10 thyroid/parathyroid:6.97 adrenal gland:6.65 pancreas:6.57 breast:6.56 salivary:6.78
CAGE uterus:2.72 placenta:2.48 prostate:3.15 ovary:2.64 testis:2.18 heart:3.78 muscle:3.79 esophagus:3.49 stomach:- intestine:2.41 colon:3.23     liver/hepato:3.34    lung:3.35 bladder:2.90 kidney:4.21 pituitary:4.41 thyroid/parathyroid:3.68 adrenal gland:- pancreas:3.13 breast:3.71 salivary:2.99
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.07 testis:1.17 heart:0.88 muscle:0.49 esophagus:- stomach:- intestine:- colon:0.22     liver/hepato:0.43        lung:1.39    bladder:- kidney:0.36 pituitary:- thyroid/parathyroid:0.46 adrenal gland:0.06 pancreas:- breast:0.76 salivary:-

Gene Information

IDs

Refseq ID NM_001114138
Gene ID 2039
Unigene ID Hs.106124
Probe set ID 204505_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000158856
GTEx ID ENSG00000158856

Orthologous Gene

Mouse[2]  NM_013514
Rat [0]  

Chromosomal Region

8p21.3  [21,906,506  -  21,940,038]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7615546
8341682
8608138
10565303
12011427
12477932
14623284
14660664
14702039
15489334
16169070
16344560
16697408
18029348
18347014
18541383
19030997
19241372
19953087
20396930
21832049
22927433
23060452
23355471
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0051017  actin filament bundle formation
GO:0051693  actin filament capping
GO:0071277  cellular response to calcium ion
GO:0071320  cellular response to cAMP
GO:0007010  cytoskeleton organization
GO:0048821  erythrocyte development
GO:0010812  negative regulation of cell-substrate adhesion
GO:0051895  negative regulation of focal adhesion formation
GO:0033137  negative regulation of peptidyl-serine phosphorylation
GO:0010801  negative regulation of peptidyl-threonine phosphorylation
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0030194  positive regulation of blood coagulation
GO:0010763  positive regulation of fibroblast migration
GO:0006461  protein complex assembly
GO:0070560  protein secretion by platelet
GO:0032956  regulation of actin cytoskeleton organization
GO:0008360  regulation of cell shape
GO:0051489  regulation of filopodium assembly
GO:0010591  regulation of lamellipodium assembly

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005884  actin filament
GO:0031253  cell projection membrane
GO:0030863  cortical cytoskeleton
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0031095  platelet dense tubular network membrane
GO:0014731  spectrin-associated cytoskeleton

Molecular Function

GO:0003779  actin binding
GO:0005515  protein binding
GO:0043621  protein self-association
GO:0005102  receptor binding
GO:0030507  spectrin binding