nuclear receptor subfamily 2, group F, member 6

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Synonym

nuclear receptor subfamily 2, group F, member 6, EAR2, Orphan nuclear receptor EAR-2, ERBAL2, NR2F6, EAR-2, V-erbA-related protein EAR-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.70 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:129.30 artery/aorta:- vein:- lymphnode:50.60 peripheral blood:- spleen:18.90 thymus:25.80 bone marrow:- adipose:- bone:12.80 skin:14.40
GeneChip cerebrum:6.47 cerebellum:6.82 brain stem:6.48 corpus callosum/glia:5.71 pineal gland:- peripheral nerve:6.24 spine:5.84 retina:- eye:- artery/aorta:6.75 vein:6.18 lymphnode:6.15 peripheral blood:- spleen:5.77 thymus:5.44 bone marrow:5.15 adipose:6.89 bone:- skin:6.99
CAGE cerebrum:1.94 cerebellum:- brain stem:1.79 corpus callosum/glia:1.95 pineal gland:2.53 peripheral nerve:- spine:1.59 retina:- eye:- artery/aorta:2.77 vein:2.46 lymphnode:2.20 peripheral blood:- spleen:2.06 thymus:1.33 bone marrow:- adipose:2.50 bone:- skin:-
RNA-seq cerebrum:2.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:32.80 prostate:123.90 ovary:- testis:30.30 heart:51.10 muscle:- esophagus:- stomach:42.50 intestine:- colon:8.50     liver/hepato:10.60        lung:39.10    bladder:- kidney:124.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:83.60 salivary:-
GeneChip uterus:6.87 placenta:7.84 prostate:6.96 ovary:6.76 testis:6.65 heart:6.90 muscle:7.02 esophagus:7.66 stomach:7.40 intestine:7.36 colon:7.76 liver/hepato:8.44 lung:6.76 bladder:- kidney:7.63 pituitary:6.77 thyroid/parathyroid:7.19 adrenal gland:6.89 pancreas:6.93 breast:7.30 salivary:7.48
CAGE uterus:2.61 placenta:3.74 prostate:2.99 ovary:2.75 testis:2.72 heart:2.65 muscle:2.95 esophagus:3.39 stomach:- intestine:3.98 colon:3.75     liver/hepato:4.08    lung:2.96 bladder:2.64 kidney:3.24 pituitary:1.67 thyroid/parathyroid:3.08 adrenal gland:- pancreas:3.61 breast:3.19 salivary:3.15
RNA-seq uterus:- placenta:- prostate:3.67 ovary:4.02 testis:3.43 heart:3.48 muscle:3.31 esophagus:- stomach:- intestine:- colon:3.79     liver/hepato:4.88        lung:3.43    bladder:- kidney:4.26 pituitary:- thyroid/parathyroid:3.53 adrenal gland:3.08 pancreas:- breast:4.44 salivary:-

Gene Information

IDs

Refseq ID NM_005234
Gene ID 2063
Unigene ID Hs.466148
Probe set ID 209262_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000160113
GTEx ID ENSG00000160113

Orthologous Gene

Mouse[4]  NM_010150
Rat[2]  NM_139113

Chromosomal Region

19p13.11  [17,342,694  -  17,356,151]

Gene Family (Interpro ID)

IPR001723  Steroid hormone receptor
IPR003068  Transcription factor COUP
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

2905047
9226381
10318855
10644740
10713182
12477932
12690040
15302935
15489334
15604093
19505873
20195357
21247419
21696885
21890473
21906983
21963094
23975195

Gene Ontology  (GO ID)

Biological Process

GO:0050965  detection of temperature stimulus involved in sensory perception of pain
GO:0043153  entrainment of circadian clock by photoperiod
GO:0010467  gene expression
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048666  neuron development
GO:0007165  signal transduction
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0004887  thyroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding