excision repair cross-complementing rodent repair deficiency, complementation group 5

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Synonym

XPGC, ERCM2, ERCC5, UVDR, DNA excision repair protein ERCC-5, XPG, DNA-repair protein complementing XP-G cells

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:75.80

cerebellum:88.20

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:-

spine:-

retina:118.60

eye:88.20

artery/aorta:30

vein:-

lymphnode:141.50

peripheral blood:18.20

spleen:132.30

thymus:128.80

bone marrow:39.40

adipose:40.30

bone:115.20

skin:43.20

GeneChip

cerebrum:5.99

cerebellum:5.79

brain stem:6.19

corpus callosum/glia:6.05

pineal gland:-

peripheral nerve:6.25

spine:5.66

retina:-

eye:-

artery/aorta:6.72

vein:6.01

lymphnode:7.01

peripheral blood:-

spleen:6.89

thymus:7.41

bone marrow:6.32

adipose:6.61

bone:-

skin:6.66

CAGE

cerebrum:1.38

cerebellum:-

brain stem:1.46

corpus callosum/glia:1.41

pineal gland:1.55

peripheral nerve:-

spine:1.74

retina:-

eye:-

artery/aorta:1.57

vein:1.44

lymphnode:1.41

peripheral blood:-

spleen:1.39

thymus:1.91

bone marrow:-

adipose:1.25

bone:-

skin:-

RNA-seq

cerebrum:2.87

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.38

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.50

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:164

placenta:14.60

prostate:90.10

ovary:111.80

testis:138.40

heart:76.60

muscle:60.30

esophagus:-

stomach:127.50

intestine:32.40

colon:76.30

liver/hepato:52.80

lung:102.60

bladder:125.60

kidney:52

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:-

pancreas:8.90

breast:65.10

salivary:-

GeneChip

uterus:6.60

placenta:5.87

prostate:7

ovary:6.75

testis:6.64

heart:6.06

muscle:5.87

esophagus:6.54

stomach:6.40

intestine:6.14

colon:5.69

liver/hepato:6.75

lung:6.21

bladder:-

kidney:5.95

pituitary:6.53

thyroid/parathyroid:6.54

adrenal gland:6.85

pancreas:5.82

breast:6.47

salivary:6.12

CAGE

uterus:1.82

placenta:0.92

prostate:1.49

ovary:1.81

testis:1.33

heart:1.31

muscle:1.46

esophagus:1.62

stomach:-

intestine:1.13

colon:0.69

liver/hepato:1.41

lung:1.37

bladder:1.62

kidney:1.17

pituitary:1.72

thyroid/parathyroid:1.57

adrenal gland:-

pancreas:1.21

breast:1.16

salivary:1.49

RNA-seq

uterus:-

placenta:-

prostate:3.44

ovary:3.16

testis:3.58

heart:1.81

muscle:2.97

esophagus:-

stomach:-

intestine:-

colon:3.20

liver/hepato:2.41

lung:3.19

bladder:-

kidney:2.73

pituitary:-

thyroid/parathyroid:3.71

adrenal gland:3.99

pancreas:-

breast:3.56

salivary:-

IDs

Refseq ID	NM_000123
Gene ID	2073
Unigene ID	Hs.258429
Probe set ID	202414_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134899
GTEx ID	ENSG00000134899

Orthologous Gene

Mouse[1]	NM_011729
Rat[1]	NM_001106910

Chromosomal Region

13q33.1 [103,459,705 - 103,528,345]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006084	DNA repair protein (XPGC)/yeast Rad
IPR001044	Xeroderma pigmentosum group G protein

Gene Ontology (GO ID)

Biological Process

GO:0006281	DNA repair
GO:0043066	negative regulation of apoptosis
GO:0006289	nucleotide-excision repair
GO:0000718	nucleotide-excision repair, DNA damage removal
GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0009411	response to UV
GO:0010225	response to UV-C
GO:0006283	transcription-coupled nucleotide-excision repair
GO:0009650	UV protection

Cellular Component

GO:0016591	DNA-directed RNA polymerase II, holoenzyme
GO:0005675	holo TFIIH complex
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0000405	bubble DNA binding
GO:0003690	double-stranded DNA binding
GO:0004520	endodeoxyribonuclease activity
GO:0004519	endonuclease activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0047485	protein N-terminus binding
GO:0003697	single-stranded DNA binding

excision repair cross-complementing rodent repair deficiency, complementation group 5

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function