eyes absent homolog 1 (Drosophila)

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Synonym

eyes absent homolog 1 (Drosophila), MGC141875, BOR, EYA1, eyes absent (Drosophila) homolog 1, Eyes absent homolog 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:14.20 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:214.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:- bone:25.60 skin:38.40
GeneChip cerebrum:6.09 cerebellum:5.41 brain stem:5.65 corpus callosum/glia:5.62 pineal gland:- peripheral nerve:5.61 spine:5.51 retina:- eye:- artery/aorta:5.58 vein:5.14 lymphnode:5.40 peripheral blood:- spleen:5.29 thymus:6.68 bone marrow:5.66 adipose:5.60 bone:- skin:5.23
CAGE cerebrum:1.71 cerebellum:- brain stem:1.39 corpus callosum/glia:1.67 pineal gland:3.12 peripheral nerve:- spine:0.52 retina:- eye:- artery/aorta:1.10 vein:2.31 lymphnode:0.26 peripheral blood:- spleen:0 thymus:1.98 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.11 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:33.80 ovary:- testis:21.60 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:34.20    bladder:- kidney:10.40 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.71 placenta:5.14 prostate:6.71 ovary:5.30 testis:5.25 heart:6.15 muscle:5.90 esophagus:5.40 stomach:5.32 intestine:5.41 colon:5.34 liver/hepato:5.26 lung:5.37 bladder:- kidney:5.24 pituitary:7.59 thyroid/parathyroid:5.36 adrenal gland:5.35 pancreas:5.32 breast:5.28 salivary:5.40
CAGE uterus:1.44 placenta:0.08 prostate:2.00 ovary:0.14 testis:0.43 heart:1.53 muscle:1.39 esophagus:0.86 stomach:- intestine:0.14 colon:0.56     liver/hepato:0    lung:0.78 bladder:1.35 kidney:0.08 pituitary:3.76 thyroid/parathyroid:0.64 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.22 ovary:0 testis:0.04 heart:0.08 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.13 adrenal gland:0.00 pancreas:- breast:0.04 salivary:-

Gene Information

IDs

Refseq ID NM_000503
Gene ID 2138
Unigene ID Hs.491997
Probe set ID 214608_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000104313
GTEx ID ENSG00000104313

Orthologous Gene

Mouse[1]  NM_010164
Rat[1]  NM_010164

Chromosomal Region

8q13.3  [72,109,668  -  72,274,467]

Gene Family (Interpro ID)

IPR006545  EYA
IPR005834  Haloacid dehalogenase-like hydrolase

Link to Pubmed  (Pubmed ID)

2154751
7829101
8889548
9020840
9359046
9361030
9428512
9603436
9853969
10464653
10490620
10655545
10991693
11409867
11558900
11683347
11734542
11950062
12070080
12404110
12477932
12500905
12701758
12874121
15141091
15226428
15489334
15492887
15493068
16005355
16344560
16441263
16691597
16797546
17049623
17637804
17903308
18065799
18220287
19206155
19213029
19234442
19240061
19497856
19667416
19789318
20209935
20301554
20634891
20956555
20979191
21280147
21955869
22447252
23144326
23263983
23506628
23636126
23793025
23840632
24752894

Gene Ontology  (GO ID)

Biological Process

GO:0009653  anatomical structure morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0034613  cellular protein localization
GO:0090103  cochlea morphogenesis
GO:0006302  double-strand break repair
GO:0048704  embryonic skeletal system morphogenesis
GO:0000132  establishment of mitotic spindle orientation
GO:0035088  establishment or maintenance of apical/basal cell polarity
GO:0016576  histone dephosphorylation
GO:0060487  lung epithelial cell differentiation
GO:0001656  metanephros development
GO:0042474  middle ear morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0048665  neuron fate specification
GO:0042473  outer ear morphogenesis
GO:0003151  outflow tract morphogenesis
GO:0007389  pattern specification process
GO:0060037  pharyngeal system development
GO:0045739  positive regulation of DNA repair
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045747  positive regulation of Notch signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0016925  protein sumoylation
GO:0045664  regulation of neuron differentiation
GO:0010212  response to ionizing radiation
GO:0048752  semicircular canal morphogenesis
GO:0007605  sensory perception of sound
GO:0014706  striated muscle tissue development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0004725  protein tyrosine phosphatase activity