acyl-CoA synthetase long-chain family member 1

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Synonym

Acyl-CoA synthetase 1, FACL2, Long-chain acyl-CoA synthetase 2, ACSL1, Long-chain acyl-CoA synthetase 1, LACS, LACS 2, acyl-CoA synthetase long-chain family member 1, LACS 1, Long-chain-fatty-acid--CoA ligase 1, FACL1, Long-chain fatty acid CoA ligase 2, ACS1, LACS2, Palmitoyl-CoA ligase 2, LACS1, Palmitoyl-CoA ligase 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:90.10 cerebellum:50.40 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:112.30 retina:- eye:70.50 artery/aorta:- vein:- lymphnode:91 peripheral blood:72.90 spleen:56.70 thymus:51.50 bone marrow:373.90 adipose:484 bone:76.80 skin:211.20
GeneChip cerebrum:7.04 cerebellum:5.82 brain stem:7.34 corpus callosum/glia:8.19 pineal gland:- peripheral nerve:7.42 spine:8.05 retina:- eye:- artery/aorta:8.30 vein:7.29 lymphnode:6.54 peripheral blood:- spleen:6.92 thymus:6.26 bone marrow:9.12 adipose:10.92 bone:- skin:9.65
CAGE cerebrum:3.72 cerebellum:- brain stem:4.47 corpus callosum/glia:4.63 pineal gland:3.93 peripheral nerve:- spine:4.90 retina:- eye:- artery/aorta:4.24 vein:4.40 lymphnode:4.17 peripheral blood:- spleen:4.43 thymus:2.53 bone marrow:- adipose:6.14 bone:- skin:-
RNA-seq cerebrum:5.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:32.80 prostate:101.40 ovary:111.80 testis:190.40 heart:51.10 muscle:321.40 esophagus:- stomach:- intestine:- colon:33.90     liver/hepato:380        lung:293.30    bladder:- kidney:166.40 pituitary:- thyroid/parathyroid:- adrenal gland:253.90 pancreas:44.50 breast:130.10 salivary:-
GeneChip uterus:7 placenta:5.23 prostate:9.43 ovary:6.31 testis:6.05 heart:9.09 muscle:9.81 esophagus:8.19 stomach:7.16 intestine:7.48 colon:6.41 liver/hepato:11 lung:8.16 bladder:- kidney:9.33 pituitary:6.77 thyroid/parathyroid:7.71 adrenal gland:7.13 pancreas:6.54 breast:8.64 salivary:8.78
CAGE uterus:3.35 placenta:2.64 prostate:3.65 ovary:3.32 testis:3.97 heart:4.81 muscle:5.59 esophagus:3.96 stomach:- intestine:2.97 colon:3.92     liver/hepato:6.74    lung:4.73 bladder:3.84 kidney:5.11 pituitary:3.88 thyroid/parathyroid:3.90 adrenal gland:- pancreas:2.98 breast:5.87 salivary:4.67
RNA-seq uterus:- placenta:- prostate:4.46 ovary:3.76 testis:4.79 heart:6.80 muscle:6.64 esophagus:- stomach:- intestine:- colon:4.27     liver/hepato:9.13        lung:5.31    bladder:- kidney:6.98 pituitary:- thyroid/parathyroid:6.12 adrenal gland:4.09 pancreas:- breast:8.68 salivary:-

Gene Information

IDs

Refseq ID NM_001995
Gene ID 2180
Unigene ID Hs.406678
Probe set ID 201963_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000151726
GTEx ID ENSG00000151726

Orthologous Gene

Mouse[3]  NM_007981
Rat [0]  

Chromosomal Region

4q35.1  [185,676,749  -  185,747,972]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1531127
1599407
1607358
2007410
2341402
2973813
7429333
7490105
7948012
8399326
8584017
8889548
8944226
10548543
12477932
14702039
15292367
15489334
16054041
16834775
17255364
18660489
19946888
20176858
20877624
21139048
21890473
21906983
21963094
21988832
22797925
22829935
22990118
23000965
23303383
23433401
23503661
24462768
24503477

Gene Ontology  (GO ID)

Biological Process

GO:0033211  adiponectin-mediated signaling pathway
GO:0044255  cellular lipid metabolic process
GO:0043651  linoleic acid metabolic process
GO:0008610  lipid biosynthetic process
GO:0001676  long-chain fatty acid metabolic process
GO:0042493  response to drug
GO:0007584  response to nutrient
GO:0034201  response to oleic acid
GO:0014070  response to organic cyclic substance
GO:0019432  triglyceride biosynthetic process
GO:0033559  unsaturated fatty acid metabolic process
GO:0042178  xenobiotic catabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion
GO:0005778  peroxisomal membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0004467  long-chain-fatty-acid-CoA ligase activity