smoothelin-like 1

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Synonym

CHASM, smoothelin-like 1, SMTNL1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip nodata
CAGE nodata
RNA-seq cerebrum:0.26 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.04 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:38.30 muscle:281.30 esophagus:- stomach:- intestine:- colon:-     liver/hepato:42.20        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE nodata
RNA-seq uterus:- placenta:- prostate:0.03 ovary:0.13 testis:0.87 heart:0.04 muscle:6.37 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.11        lung:0.18    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:2.61 adrenal gland:0.40 pancreas:- breast:2.48 salivary:-

Gene Information

IDs

Refseq ID NM_001105565
Gene ID 219537
Unigene ID Hs.68756
Probe set ID -
Ensembl ID ENSG00000214872
GTEx ID ENSG00000214872

Orthologous Gene

Mouse[1]  NM_024230
Rat [0]  

Chromosomal Region

11q12.1  [57,308,979  -  57,318,108]

Gene Family (Interpro ID)

IPR016146  Calponin-homology
IPR001715  Calponin-like actin-binding

Link to Pubmed  (Pubmed ID)

8889549
15327999
18310078
20634291
21352594

Gene Ontology  (GO ID)

Biological Process

GO:0045908  negative regulation of vasodilation
GO:0045907  positive regulation of vasoconstriction

Cellular Component

GO:0043292  contractile fiber
GO:0005737  cytoplasm
GO:0031674  I band
GO:0031430  M band
GO:0005634  nucleus

Molecular Function

GO:0005516  calmodulin binding