fibroblast growth factor 1 (acidic)

Synonym

ECGFA, HBGF1, FGFA, ECGF-beta, Beta-endothelial cell growth factor, HBGF-1, ECGF, AFGF, ECGFB, FGF-alpha, FGF1, aFGF, Acidic fibroblast growth factor, GLIO703, Heparin-binding growth factor 1 precursor, fibroblast growth factor 1 (acidic)

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:356.70

cerebellum:440.80

brain stem:-

corpus callosum/glia:116.60

pineal gland:-

peripheral nerve:30.70

spine:224.60

retina:-

eye:52.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:18.90

thymus:-

bone marrow:-

adipose:121

bone:12.80

skin:48

GeneChip

cerebrum:9.25

cerebellum:8.08

brain stem:9.79

corpus callosum/glia:10.42

pineal gland:-

peripheral nerve:9.49

spine:10

retina:-

eye:-

artery/aorta:6.99

vein:6.22

lymphnode:4.89

peripheral blood:-

spleen:5.78

thymus:5.16

bone marrow:5.37

adipose:6.33

bone:-

skin:5.27

CAGE

cerebrum:4.85

cerebellum:-

brain stem:5.87

corpus callosum/glia:6.18

pineal gland:3.12

peripheral nerve:-

spine:5.35

retina:-

eye:-

artery/aorta:3.42

vein:1.92

lymphnode:0.88

peripheral blood:-

spleen:1.39

thymus:0.71

bone marrow:-

adipose:2.58

bone:-

skin:-

RNA-seq

cerebrum:4.80

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.69

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:-

ovary:-

testis:8.70

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:31.70

lung:34.20

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:158

salivary:-

GeneChip

uterus:5.50

placenta:4.92

prostate:5.46

ovary:4.93

testis:5.67

heart:6.82

muscle:5.34

esophagus:5.27

stomach:4.83

intestine:5.23

colon:5.04

liver/hepato:4.92

lung:5.15

bladder:-

kidney:7.63

pituitary:6.67

thyroid/parathyroid:5.30

adrenal gland:5.17

pancreas:4.79

breast:6.46

salivary:5.55

CAGE

uterus:1.31

placenta:0.59

prostate:1.38

ovary:0.47

testis:1.09

heart:3.40

muscle:1.74

esophagus:1.44

stomach:-

intestine:0.87

colon:0.93

liver/hepato:0.78

lung:1.02

bladder:0.98

kidney:4.11

pituitary:2.50

thyroid/parathyroid:0.95

adrenal gland:-

pancreas:0

breast:2.27

salivary:2.66

RNA-seq

uterus:-

placenta:-

prostate:0.58

ovary:0.26

testis:0.46

heart:1.88

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.65

liver/hepato:0.12

lung:0.00

bladder:-

kidney:4.32

pituitary:-

thyroid/parathyroid:0.15

adrenal gland:0.28

pancreas:-

breast:2.62

salivary:-

IDs

Refseq ID	NM_033137
Gene ID	2246
Unigene ID	Hs.483635
Probe set ID	205117_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000113578
GTEx ID	ENSG00000113578

Orthologous Gene

Mouse[2]	NM_010197
Rat [0]

Chromosomal Region

5q31.3 [141,971,743 - 142,077,617]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008996	Cytokine, IL-1-like
IPR002209	Heparin-binding growth factor/Fibroblast growth factor
IPR002348	Interleukin 1/heparin-binding growth factor

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0001525	angiogenesis
GO:0060681	branch elongation involved in ureteric bud branching
GO:0034605	cellular response to heat
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0001759	induction of an organ
GO:0045087	innate immune response
GO:0008286	insulin receptor signaling pathway
GO:0030324	lung development
GO:0007275	multicellular organismal development
GO:0048011	nerve growth factor receptor signaling pathway
GO:0048015	phosphoinositide-mediated signaling
GO:0045766	positive regulation of angiogenesis
GO:0051781	positive regulation of cell division
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0045542	positive regulation of cholesterol biosynthetic process
GO:0050679	positive regulation of epithelial cell proliferation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0010740	positive regulation of protein kinase cascade
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0007165	signal transduction

Cellular Component

GO:0005938	cell cortex
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005730	nucleolus
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0005104	fibroblast growth factor receptor binding
GO:0008083	growth factor activity
GO:0008201	heparin binding
GO:0030544	Hsp70 protein binding
GO:0005515	protein binding

fibroblast growth factor 1 (acidic)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function