fibroblast growth factor 8 (androgen-induced)

 jump to detail

Synonym

fibroblast growth factor 8 (androgen-induced), FGF-8, AIGF, Fibroblast growth factor 8 precursor, FGF8, HBGF-8, Androgen-induced growth factor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.09 cerebellum:3.20 brain stem:3.16 corpus callosum/glia:3.04 pineal gland:- peripheral nerve:2.92 spine:2.92 retina:- eye:- artery/aorta:3.36 vein:3.09 lymphnode:3.30 peripheral blood:- spleen:2.96 thymus:3.04 bone marrow:3.21 adipose:3.27 bone:- skin:3.63
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0.18 lymphnode:0 peripheral blood:- spleen:0 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.10 placenta:3.11 prostate:3.12 ovary:3.20 testis:3.02 heart:2.97 muscle:3.23 esophagus:3.27 stomach:3.17 intestine:3.36 colon:3.22 liver/hepato:3.19 lung:3.19 bladder:- kidney:3.18 pituitary:3.13 thyroid/parathyroid:3.10 adrenal gland:3.35 pancreas:3.79 breast:3.19 salivary:3.27
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0.16 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0.06 salivary:-

Gene Information

IDs

Refseq ID NM_033164
Gene ID 2253
Unigene ID Hs.57710
Probe set ID 208449_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107831
GTEx ID ENSG00000107831

Orthologous Gene

Mouse[4]  NM_001166361, NM_001166362, NM_001166363, NM_010205
Rat[4]  NM_001166361, NM_001166362, NM_001166363, NM_010205

Chromosomal Region

10q24.32  [103,530,081  -  103,535,827]

Gene Family (Interpro ID)

IPR008996  Cytokine, IL-1-like
IPR002348  Interleukin 1/heparin-binding growth factor

Link to Pubmed  (Pubmed ID)

7737407
8595889
8661131
8663044
8700553
8891346
9139660
9332670
10574949
10579907
10736564
10751172
11021964
11294897
11341643
11358849
11420691
11953856
12054865
12140757
12477932
12778074
15146197
15193767
15199049
15935652
16384934
16597617
16683270
17133345
17264867
17265164
17309880
17394220
17512240
17600781
18386787
18437684
18596921
19415685
20301509
20301702
20463092
20634891
21034500
21048031
21076617
21119603
21319186
21832120
22237711
22319038
22423049
23466786
23533228
23906837
24464787

Gene Ontology  (GO ID)

Biological Process

GO:0060128  adrenocorticotropin hormone secreting cell differentiation
GO:0009653  anatomical structure morphogenesis
GO:0006915  apoptosis
GO:0001974  blood vessel remodeling
GO:0030509  BMP signaling pathway
GO:0060348  bone development
GO:0060445  branching involved in salivary gland morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0090134  cell migration involved in mesendoderm migration
GO:0021846  cell proliferation in forebrain
GO:0035116  embryonic hindlimb morphogenesis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0003198  epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0021798  forebrain dorsal/ventral pattern formation
GO:0048853  forebrain morphogenesis
GO:0007369  gastrulation
GO:0008406  gonad development
GO:0001947  heart looping
GO:0001759  induction of an organ
GO:0045087  innate immune response
GO:0008286  insulin receptor signaling pathway
GO:0060425  lung morphogenesis
GO:0030539  male genitalia development
GO:0000165  MAPKKK cascade
GO:0008078  mesodermal cell migration
GO:0001823  mesonephros development
GO:0001656  metanephros development
GO:0030917  midbrain-hindbrain boundary development
GO:0055026  negative regulation of cardiac muscle tissue development
GO:0043524  negative regulation of neuron apoptosis
GO:0048011  nerve growth factor receptor signaling pathway
GO:0001839  neural plate morphogenesis
GO:0060563  neuroepithelial cell differentiation
GO:0042476  odontogenesis
GO:0030916  otic vesicle formation
GO:0003148  outflow tract septum morphogenesis
GO:0021543  pallium development
GO:0001569  patterning of blood vessels
GO:0060037  pharyngeal system development
GO:0048015  phosphoinositide-mediated signaling
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0045840  positive regulation of mitosis
GO:0046622  positive regulation of organ growth
GO:0042487  regulation of odontogenesis of dentine-containing tooth
GO:0021544  subpallium development
GO:0030878  thyroid gland development
GO:0060129  thyroid stimulating hormone secreting cell differentiation
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0008083  growth factor activity
GO:0005105  type 1 fibroblast growth factor receptor binding
GO:0005111  type 2 fibroblast growth factor receptor binding