fibroblast growth factor 9 (glia-activating factor)

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Synonym

Glia-activating factor precursor, HBGF-9, GAF, MGC119914, Fibroblast growth factor 9, FGF-9, FGF9, MGC119915, HBFG-9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:99.90 artery/aorta:30 vein:199.90 lymphnode:- peripheral blood:- spleen:37.80 thymus:25.80 bone marrow:- adipose:- bone:- skin:67.20
GeneChip cerebrum:6.85 cerebellum:9.04 brain stem:6.80 corpus callosum/glia:4.77 pineal gland:- peripheral nerve:7.70 spine:5.98 retina:- eye:- artery/aorta:5.54 vein:6.14 lymphnode:4.97 peripheral blood:- spleen:4.55 thymus:5.08 bone marrow:4.78 adipose:5.51 bone:- skin:4.53
CAGE cerebrum:2.02 cerebellum:- brain stem:1.55 corpus callosum/glia:0.76 pineal gland:0.36 peripheral nerve:- spine:0.89 retina:- eye:- artery/aorta:1.22 vein:0.88 lymphnode:0.32 peripheral blood:- spleen:0.45 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:1.82 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.21 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:47.40 prostate:- ovary:- testis:17.30 heart:102.20 muscle:- esophagus:- stomach:212.40 intestine:- colon:67.80     liver/hepato:42.20        lung:29.30    bladder:251.20 kidney:41.60 pituitary:116 thyroid/parathyroid:163.70 adrenal gland:- pancreas:62.20 breast:74.30 salivary:-
GeneChip uterus:6.22 placenta:4.70 prostate:4.78 ovary:5.48 testis:5.51 heart:6.68 muscle:5.73 esophagus:5.15 stomach:5.74 intestine:5.35 colon:5.54 liver/hepato:4.47 lung:5.79 bladder:- kidney:8.51 pituitary:6.44 thyroid/parathyroid:4.84 adrenal gland:7.54 pancreas:4.47 breast:4.73 salivary:4.96
CAGE uterus:1.13 placenta:0.08 prostate:0.49 ovary:1.37 testis:0.55 heart:1.51 muscle:0.09 esophagus:0.73 stomach:- intestine:0.77 colon:1.48     liver/hepato:0    lung:1.16 bladder:1.52 kidney:2.05 pituitary:2.62 thyroid/parathyroid:0.12 adrenal gland:- pancreas:1.42 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:0.86 ovary:1.00 testis:0.97 heart:0.73 muscle:0.11 esophagus:- stomach:- intestine:- colon:0.26     liver/hepato:0.00        lung:0.46    bladder:- kidney:2.42 pituitary:- thyroid/parathyroid:0.33 adrenal gland:0.09 pancreas:- breast:0.21 salivary:-

Gene Information

IDs

Refseq ID NM_002010
Gene ID 2254
Unigene ID Hs.11108
Probe set ID 206404_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000102678
GTEx ID ENSG00000102678

Orthologous Gene

Mouse[2]  NM_013518
Rat [0]  

Chromosomal Region

13q12.11  [22,245,522  -  22,278,637]

Gene Family (Interpro ID)

IPR008996  Cytokine, IL-1-like
IPR002209  Heparin-binding growth factor/Fibroblast growth factor
IPR002348  Interleukin 1/heparin-binding growth factor

Link to Pubmed  (Pubmed ID)

1697263
8321227
8428960
8575785
8576175
8663044
9121694
9139660
9507114
10362017
10544294
10574949
10579907
11060292
11223514
11294897
12072406
12477932
12565813
12660731
14534538
14602803
14702039
15057823
15199049
15489334
15780951
16540513
16597617
16982695
17133345
17154280
17848411
18165946
18593907
18618013
19460469
19564416
19589401
20424473
20634891
20819778
21048031
21499246
21666490
22006051
22920789
22939835
23291589
23727932
23797050
23898208
24011613
24015269
24334956
24511001

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0007267  cell-cell signaling
GO:0002062  chondrocyte differentiation
GO:0048566  embryonic gut development
GO:0030326  embryonic limb morphogenesis
GO:0048706  embryonic skeletal system development
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0045087  innate immune response
GO:0042472  inner ear morphogenesis
GO:0008286  insulin receptor signaling pathway
GO:0060484  lung-associated mesenchyme development
GO:0008584  male gonad development
GO:0030238  male sex determination
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0048011  nerve growth factor receptor signaling pathway
GO:0001649  osteoblast differentiation
GO:0048015  phosphoinositide-mediated signaling
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0051781  positive regulation of cell division
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0010628  positive regulation of gene expression
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045880  positive regulation of smoothened signaling pathway
GO:0030949  positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0006606  protein import into nucleus
GO:0048505  regulation of timing of cell differentiation
GO:0007165  signal transduction

Cellular Component

GO:0005604  basement membrane
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005104  fibroblast growth factor receptor binding
GO:0008083  growth factor activity
GO:0008201  heparin binding