fibroblast growth factor 13

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Synonym

FHF2, Fibroblast growth factor homologous factor 2, FHF-2, FGF-13, fibroblast growth factor 13, FGF13, Fibroblast growth factor 13, FGF2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:112.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:47 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:56.70 thymus:- bone marrow:- adipose:40.30 bone:- skin:-
GeneChip cerebrum:7.78 cerebellum:4.46 brain stem:7.05 corpus callosum/glia:4.88 pineal gland:- peripheral nerve:10 spine:6.47 retina:- eye:- artery/aorta:6.46 vein:6.35 lymphnode:5.06 peripheral blood:- spleen:5.90 thymus:4.16 bone marrow:5.24 adipose:6.36 bone:- skin:5.23
CAGE cerebrum:3.27 cerebellum:- brain stem:1.30 corpus callosum/glia:1.80 pineal gland:2.81 peripheral nerve:- spine:1.83 retina:- eye:- artery/aorta:2.73 vein:1.65 lymphnode:1.58 peripheral blood:- spleen:1.93 thymus:0.28 bone marrow:- adipose:2.60 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.09 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:7.30 prostate:- ovary:37.30 testis:4.30 heart:- muscle:- esophagus:- stomach:148.70 intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:46.50 salivary:-
GeneChip uterus:6.54 placenta:5.95 prostate:7.56 ovary:5.28 testis:5.12 heart:4.72 muscle:7.70 esophagus:5.14 stomach:5.47 intestine:6.13 colon:5.76 liver/hepato:3.79 lung:4.79 bladder:- kidney:5.35 pituitary:5.62 thyroid/parathyroid:5.78 adrenal gland:4.58 pancreas:4.84 breast:5.79 salivary:6.71
CAGE uterus:2.54 placenta:2.19 prostate:3.30 ovary:1.62 testis:2.21 heart:1.39 muscle:3.57 esophagus:1.91 stomach:- intestine:1.76 colon:1.94     liver/hepato:0.63    lung:0.84 bladder:1.89 kidney:2.57 pituitary:1.82 thyroid/parathyroid:2.03 adrenal gland:- pancreas:0.94 breast:2.41 salivary:2.88
RNA-seq uterus:- placenta:- prostate:1.03 ovary:0.20 testis:0.74 heart:0.19 muscle:1.21 esophagus:- stomach:- intestine:- colon:0.84     liver/hepato:0.00        lung:0.44    bladder:- kidney:0.95 pituitary:- thyroid/parathyroid:0.94 adrenal gland:0.10 pancreas:- breast:1.77 salivary:-

Gene Information

IDs

Refseq ID NM_001139498
Gene ID 2258
Unigene ID Hs.6540
Probe set ID 205110_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000129682
GTEx ID ENSG00000129682

Orthologous Gene

Mouse[2]  NM_010200
Rat [0]  

Chromosomal Region

Xq27.1  [137,713,735  -  138,304,939]

Gene Family (Interpro ID)

IPR008996  Cytokine, IL-1-like
IPR002209  Heparin-binding growth factor/Fibroblast growth factor
IPR002348  Interleukin 1/heparin-binding growth factor

Link to Pubmed  (Pubmed ID)

8790420
9751161
9847253
9914447
10071193
10644718
11847221
12244047
12477932
12496262
15199049
15282281
15489334
18482256
21163940
23006423
23603273
24113164

Gene Ontology  (GO ID)

Biological Process

GO:0007267  cell-cell signaling
GO:0021795  cerebral cortex cell migration
GO:0045200  establishment of neuroblast polarity
GO:0021766  hippocampus development
GO:0007612  learning
GO:0000165  MAPKKK cascade
GO:0007613  memory
GO:0046785  microtubule polymerization
GO:0048671  negative regulation of collateral sprouting
GO:0007026  negative regulation of microtubule depolymerization
GO:0007399  nervous system development
GO:0001764  neuron migration
GO:0045860  positive regulation of protein kinase activity
GO:0007165  signal transduction

Cellular Component

GO:0030424  axon
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0030175  filopodium
GO:0030426  growth cone
GO:0014704  intercalated disc
GO:0005874  microtubule
GO:0043005  neuron projection
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0048487  beta-tubulin binding
GO:0008083  growth factor activity
GO:0008017  microtubule binding
GO:0005515  protein binding
GO:0030295  protein kinase activator activity
GO:0017080  sodium channel regulator activity