fibroblast growth factor receptor 1

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Synonym

CEK, bFGF-R, N-SAM, KAL2, HBGFR, Fms-like tyrosine kinase 2, CD331, FLT2, FGFR1, BFGFR, FGFR-1, c-fgr, CD331 antigen, FGFBR, FLG

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:109 cerebellum:403 brain stem:- corpus callosum/glia:87.50 pineal gland:148.30 peripheral nerve:184 spine:336.90 retina:- eye:182.20 artery/aorta:30 vein:266.60 lymphnode:101.10 peripheral blood:- spleen:18.90 thymus:77.30 bone marrow:137.80 adipose:80.70 bone:268.70 skin:86.40
GeneChip cerebrum:7.05 cerebellum:8.75 brain stem:7.41 corpus callosum/glia:7.09 pineal gland:- peripheral nerve:8.85 spine:8 retina:- eye:- artery/aorta:8.82 vein:8.82 lymphnode:7.32 peripheral blood:- spleen:6.54 thymus:7.11 bone marrow:6.65 adipose:8.58 bone:- skin:7.75
CAGE cerebrum:3.75 cerebellum:- brain stem:3.82 corpus callosum/glia:3.55 pineal gland:2.85 peripheral nerve:- spine:4.09 retina:- eye:- artery/aorta:5.39 vein:4.32 lymphnode:3.47 peripheral blood:- spleen:2.33 thymus:3.45 bone marrow:- adipose:4.67 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.09 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:328.10 placenta:145.70 prostate:90.10 ovary:372.60 testis:134.10 heart:63.90 muscle:20.10 esophagus:- stomach:- intestine:162 colon:59.40     liver/hepato:-        lung:141.70    bladder:- kidney:93.60 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:124.50 breast:204.40 salivary:-
GeneChip uterus:8.41 placenta:7.71 prostate:7.59 ovary:8.40 testis:7.29 heart:8.31 muscle:6.64 esophagus:7.66 stomach:7.81 intestine:7.63 colon:7.96 liver/hepato:6.15 lung:7.89 bladder:- kidney:7.13 pituitary:7.94 thyroid/parathyroid:7.43 adrenal gland:6.97 pancreas:8.31 breast:8.94 salivary:7.11
CAGE uterus:4.65 placenta:4.13 prostate:4.59 ovary:4.92 testis:4.16 heart:4.51 muscle:3.61 esophagus:4.31 stomach:- intestine:3.18 colon:4.17     liver/hepato:2.05    lung:4.01 bladder:4.85 kidney:3.53 pituitary:4.24 thyroid/parathyroid:3.20 adrenal gland:- pancreas:4.67 breast:4.91 salivary:3.26
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.05 testis:0.08 heart:0.00 muscle:0.26 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

IDs

Refseq ID NM_023105
Gene ID 2260
Unigene ID Hs.264887
Probe set ID 211535_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000077782
GTEx ID ENSG00000077782

Orthologous Gene

Mouse[6]  NM_001079908, NM_001079909, NM_010206
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1317750
1379697
1379698
1380281
1650441
1652059
1662973
1689310
1697263
1722570
1722683
1846977
2159626
2162671
2167437
2554327
7514169
7516330
7537362
7680645
7761103
7789168
7874169
7960240
8074689
8125298
8386828
8417497
8576175
8622701
8663044
8692946
8737680
8752212
8753773
8756477
8929854
9139660
9212826
9480847
9632781
9655399
9660748
9949182
10336501
10464310
10490103
10551883
10574949
10579907
10629055
10713090
10748122
10751172
10830168
10918587
10950949
11030354
11032250
11090629
11173846
11257130
11353842
11401320
11459840
11486033
11693202
11746971
11759058
11877385
11919391
12020352
12031912
12080186
12121226
12141425
12181353
12373339
12397010
12411316
12440521
12477932
12573278
12594223
12601080
12604616
12614330
12627230
12651930
12746216
12791257
12794748
12799194
12815057
14513299
14587039
14636241
14702039
15001591
15096041
15117958
15273729
15297314
15316024
15489334
15509650
15558020
15564375
15605412
15613419
15618886
15625620
15680705
15695515
15767480
15774903
15817662
15845591
15863030
15863034
15929978
15955231
16091423
16186508
16188231
16273093
16305343
16316338
16335952
16344560
16365308
16424058
16440004
16470795
16597617
16598308
16606836
16685373
16757108
16764984
16807070
16807244
16876430
16882753
16949906
17086194
17121884
17154279
17255109
17318851
17343269
17360555
17366557
17389761
17397528
17414280
17540176
17545628
17671674
17696196
17893707
17963255
18034870
18042549
18059337
18160472
18171671
18216705
18231572
18315732
18411303
18415014
18463157
18469019
18480409
18563556
18593464
18665077
18669637
18682503
18719360
18723471
18790757
18829480
18940940
18978678
19082464
19096867
19211868
19224897
19258500
19330026
19453261
19458078
19489874
19574212
19658100
19663702
19665973
19666467
19696444
19727229
19728793
19730683
19802384
19820032
19822079
19890272
19920251
19920824
19923290
19953087
20024612
20036812
20068287
20103604
20117945
20179196
20301509
20301628
20362962
20379614
20388777
20389085
20389169
20421966
20536592
20538960
20544801
20606682
20634891
20643727
20672350
20686451
20717167
20734064
20855522
20889570
20932831
21041608
21139048
21160078
21329481
21330321
21430024
21451043
21515689
21527526
21621521
21666686
21666749
21682876
21712446
21739604
21765395
21779335
21835001
21868365
21885851
21942441
21952621
21969607
21988832
22030335
22179561
22247553
22248288
22319038
22393163
22438050
22442730
22499828
22505724
22514272
22523080
22569333
22573348
22648708
22665522
22673519
22684217
22701738
22724017
22781593
22791819
22837387
22842457
22903848
22939624
22955284
22974441
22989054
23029290
23070782
23082000
23154428
23154548
23171834
23182986
23243019
23276709
23296701
23334987
23348274
23401445
23434054
23468956
23536707
23563700
23564461
23569208
23594707
23602568
23619603
23620752
23777766
23806793
23808822
23812909
23861540
23939983
23962428
24063890
24077455
24141780
24157794
24305876
24385678
24776567
24806303

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0060117  auditory receptor cell development
GO:0007411  axon guidance
GO:0060445  branching involved in salivary gland morphogenesis
GO:0048469  cell maturation
GO:0016477  cell migration
GO:0002062  chondrocyte differentiation
GO:0043009  chordate embryonic development
GO:0030326  embryonic limb morphogenesis
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0001701  in utero embryonic development
GO:0001759  induction of an organ
GO:0045087  innate immune response
GO:0042472  inner ear morphogenesis
GO:0008286  insulin receptor signaling pathway
GO:0060484  lung-associated mesenchyme development
GO:0000165  MAPKKK cascade
GO:0048762  mesenchymal cell differentiation
GO:0030901  midbrain development
GO:0042474  middle ear morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0048011  nerve growth factor receptor signaling pathway
GO:0021847  neuroblast division in the ventricular zone
GO:0001764  neuron migration
GO:0042473  outer ear morphogenesis
GO:0048339  paraxial mesoderm development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0045787  positive regulation of cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0043406  positive regulation of MAP kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0090080  positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045666  positive regulation of neuron differentiation
GO:0010976  positive regulation of neuron projection development
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0010518  positive regulation of phospholipase activity
GO:0010863  positive regulation of phospholipase C activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0060665  regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0045595  regulation of cell differentiation
GO:0048378  regulation of lateral mesodermal cell fate specification
GO:0007605  sensory perception of sound
GO:0001501  skeletal system development
GO:0048705  skeletal system morphogenesis
GO:0006351  transcription, DNA-dependent
GO:0001657  ureteric bud development

Cellular Component

GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0017134  fibroblast growth factor binding
GO:0005007  fibroblast growth factor receptor activity
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004713  protein tyrosine kinase activity