fibroblast growth factor receptor 1

Synonym

CEK, bFGF-R, N-SAM, KAL2, HBGFR, Fms-like tyrosine kinase 2, CD331, FLT2, FGFR1, BFGFR, FGFR-1, c-fgr, CD331 antigen, FGFBR, FLG

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:109

cerebellum:403

brain stem:-

corpus callosum/glia:87.50

pineal gland:148.30

peripheral nerve:184

spine:336.90

retina:-

eye:182.20

artery/aorta:30

vein:266.60

lymphnode:101.10

peripheral blood:-

spleen:18.90

thymus:77.30

bone marrow:137.80

adipose:80.70

bone:268.70

skin:86.40

GeneChip

cerebrum:7.05

cerebellum:8.75

brain stem:7.41

corpus callosum/glia:7.09

pineal gland:-

peripheral nerve:8.85

spine:8

retina:-

eye:-

artery/aorta:8.82

vein:8.82

lymphnode:7.32

peripheral blood:-

spleen:6.54

thymus:7.11

bone marrow:6.65

adipose:8.58

bone:-

skin:7.75

CAGE

cerebrum:3.75

cerebellum:-

brain stem:3.82

corpus callosum/glia:3.55

pineal gland:2.85

peripheral nerve:-

spine:4.09

retina:-

eye:-

artery/aorta:5.39

vein:4.32

lymphnode:3.47

peripheral blood:-

spleen:2.33

thymus:3.45

bone marrow:-

adipose:4.67

bone:-

skin:-

RNA-seq

cerebrum:0.81

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.55

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.84

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:328.10

placenta:145.70

prostate:90.10

ovary:372.60

testis:134.10

heart:63.90

muscle:20.10

esophagus:-

stomach:-

intestine:162

colon:59.40

liver/hepato:-

lung:141.70

bladder:-

kidney:93.60

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:124.50

breast:204.40

salivary:-

GeneChip

uterus:8.41

placenta:7.71

prostate:7.59

ovary:8.40

testis:7.29

heart:8.31

muscle:6.64

esophagus:7.66

stomach:7.81

intestine:7.63

colon:7.96

liver/hepato:6.15

lung:7.89

bladder:-

kidney:7.13

pituitary:7.94

thyroid/parathyroid:7.43

adrenal gland:6.97

pancreas:8.31

breast:8.94

salivary:7.11

CAGE

uterus:4.65

placenta:4.13

prostate:4.59

ovary:4.92

testis:4.16

heart:4.51

muscle:3.61

esophagus:4.31

stomach:-

intestine:3.18

colon:4.17

liver/hepato:2.05

lung:4.01

bladder:4.85

kidney:3.53

pituitary:4.24

thyroid/parathyroid:3.20

adrenal gland:-

pancreas:4.67

breast:4.91

salivary:3.26

RNA-seq

uterus:-

placenta:-

prostate:3.06

ovary:1.36

testis:0.85

heart:1.82

muscle:0.75

esophagus:-

stomach:-

intestine:-

colon:2.82

liver/hepato:0.57

lung:3.57

bladder:-

kidney:1.22

pituitary:-

thyroid/parathyroid:1.60

adrenal gland:1.89

pancreas:-

breast:2.69

salivary:-

IDs

Refseq ID	NM_023106
Gene ID	2260
Unigene ID	Hs.264887
Probe set ID	211535_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000077782
GTEx ID	ENSG00000077782

Orthologous Gene

Mouse[6]	NM_001079908, NM_001079909, NM_010206
Rat [0]

Chromosomal Region

8p11.22 [38,268,656 - 38,326,352]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0060117	auditory receptor cell development
GO:0007411	axon guidance
GO:0060445	branching involved in salivary gland morphogenesis
GO:0048469	cell maturation
GO:0016477	cell migration
GO:0002062	chondrocyte differentiation
GO:0043009	chordate embryonic development
GO:0030326	embryonic limb morphogenesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0001701	in utero embryonic development
GO:0001759	induction of an organ
GO:0045087	innate immune response
GO:0042472	inner ear morphogenesis
GO:0008286	insulin receptor signaling pathway
GO:0060484	lung-associated mesenchyme development
GO:0000165	MAPKKK cascade
GO:0048762	mesenchymal cell differentiation
GO:0030901	midbrain development
GO:0042474	middle ear morphogenesis
GO:0043066	negative regulation of apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0048011	nerve growth factor receptor signaling pathway
GO:0021847	neuroblast division in the ventricular zone
GO:0001764	neuron migration
GO:0042473	outer ear morphogenesis
GO:0048339	paraxial mesoderm development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0045787	positive regulation of cell cycle
GO:0008284	positive regulation of cell proliferation
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0045666	positive regulation of neuron differentiation
GO:0010976	positive regulation of neuron projection development
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0010518	positive regulation of phospholipase activity
GO:0010863	positive regulation of phospholipase C activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0045595	regulation of cell differentiation
GO:0048378	regulation of lateral mesodermal cell fate specification
GO:0007605	sensory perception of sound
GO:0001501	skeletal system development
GO:0048705	skeletal system morphogenesis
GO:0006351	transcription, DNA-dependent
GO:0001657	ureteric bud development

Cellular Component

GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0004713	protein tyrosine kinase activity

fibroblast growth factor receptor 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function