fibroblast growth factor receptor 4

Synonym

Fibroblast growth factor receptor 4 precursor, FGFR4, TKF, MGC20292, fibroblast growth factor receptor 4, CD334, CD334 antigen, FGFR-4, JTK2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:4.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:18.20

spleen:75.60

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:24

GeneChip

cerebrum:4.11

cerebellum:4.39

brain stem:4.09

corpus callosum/glia:4.14

pineal gland:-

peripheral nerve:4.12

spine:4.22

retina:-

eye:-

artery/aorta:4.73

vein:4.18

lymphnode:4.54

peripheral blood:-

spleen:5.45

thymus:4.28

bone marrow:4.35

adipose:4.30

bone:-

skin:4.63

CAGE

cerebrum:0.26

cerebellum:-

brain stem:0.25

corpus callosum/glia:0.52

pineal gland:0.56

peripheral nerve:-

spine:0.29

retina:-

eye:-

artery/aorta:0.18

vein:1.03

lymphnode:0.79

peripheral blood:-

spleen:2.61

thymus:0

bone marrow:-

adipose:0.14

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:37.30

testis:-

heart:51.10

muscle:20.10

esophagus:-

stomach:-

intestine:-

colon:50.90

liver/hepato:10.60

lung:39.10

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.38

placenta:4.14

prostate:4.22

ovary:4.87

testis:4.52

heart:4.12

muscle:4.57

esophagus:4.22

stomach:4.95

intestine:5.56

colon:5.55

liver/hepato:7.20

lung:6.92

bladder:-

kidney:5.93

pituitary:4.16

thyroid/parathyroid:4.25

adrenal gland:5.13

pancreas:4.29

breast:4.62

salivary:4.33

CAGE

uterus:0.98

placenta:0.68

prostate:1.69

ovary:2.78

testis:1.25

heart:0.40

muscle:0.85

esophagus:0.90

stomach:-

intestine:2.98

colon:2.79

liver/hepato:3.79

lung:3.56

bladder:0.53

kidney:3.73

pituitary:0.34

thyroid/parathyroid:0.37

adrenal gland:-

pancreas:3.32

breast:0

salivary:0.62

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:1.74

testis:0.08

heart:0.00

muscle:0.12

esophagus:-

stomach:-

intestine:-

colon:0.17

liver/hepato:1.69

lung:2.95

bladder:-

kidney:1.38

pituitary:-

thyroid/parathyroid:0.04

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_213647
Gene ID	2264
Unigene ID	Hs.165950
Probe set ID	204579_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000160867
GTEx ID	ENSG00000160867

Orthologous Gene

Mouse[2]	NM_008011
Rat[2]	NM_001109904

Chromosomal Region

5q35.2 [176,513,887 - 176,525,145]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0016477	cell migration
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0042593	glucose homeostasis
GO:0001759	induction of an organ
GO:0045087	innate immune response
GO:0008286	insulin receptor signaling pathway
GO:0048011	nerve growth factor receptor signaling pathway
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0055062	phosphate ion homeostasis
GO:0048015	phosphoinositide-mediated signaling
GO:0008284	positive regulation of cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0048554	positive regulation of metalloenzyme activity
GO:0045862	positive regulation of proteolysis
GO:0046777	protein amino acid autophosphorylation
GO:0070857	regulation of bile acid biosynthetic process
GO:0010715	regulation of extracellular matrix disassembly
GO:0019216	regulation of lipid metabolic process

Cellular Component

GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005768	endosome
GO:0005576	extracellular region
GO:0005887	integral to plasma membrane
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0017134	fibroblast growth factor binding
GO:0005007	fibroblast growth factor receptor activity
GO:0008201	heparin binding
GO:0004713	protein tyrosine kinase activity

fibroblast growth factor receptor 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function