connector enhancer of kinase suppressor of Ras 2

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Synonym

Connector enhancer of KSR2, connector enhancer of kinase suppressor of Ras 2, Connector enhancer of kinase suppressor of ras 2, CNKSR2, KIAA0902, KSR2, CNK2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:4.45 cerebellum:- brain stem:1.71 corpus callosum/glia:2.48 pineal gland:0.71 peripheral nerve:- spine:2.19 retina:- eye:- artery/aorta:1.52 vein:1.86 lymphnode:1.55 peripheral blood:- spleen:1.21 thymus:1.79 bone marrow:- adipose:1.54 bone:- skin:-
RNA-seq cerebrum:3.43 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:33.80 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:1.06 placenta:0.43 prostate:0.66 ovary:0.92 testis:0.87 heart:0.83 muscle:0.72 esophagus:0.68 stomach:- intestine:0.21 colon:0.69     liver/hepato:0.55    lung:1.56 bladder:1.12 kidney:0.27 pituitary:2.24 thyroid/parathyroid:0.37 adrenal gland:- pancreas:0.94 breast:1.36 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.55 ovary:0.33 testis:0.38 heart:0.00 muscle:1.05 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.60    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.37 adrenal gland:0.00 pancreas:- breast:0.37 salivary:-

Gene Information

IDs

Refseq ID NM_014927
Gene ID 22866
Unigene ID Hs.555917
Probe set ID -
Ensembl ID ENSG00000149970
GTEx ID ENSG00000149970

Orthologous Gene

Mouse[1]  NM_177751
Rat[4]  NM_001113366, NM_021686

Chromosomal Region

Xp22.12  [21,392,536  -  21,672,813]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

7757816
8889548
10048485
10207009
12390249
12477932
14597674
14702039
15028221
15342556
15489334
15772651
16344560
16637659
17043677
17353931
18029348
18287031
18790760
19056867
19260141
19563921
19615732

Gene Ontology  (GO ID)

Biological Process

GO:0009966  regulation of signal transduction

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0043005  neuron projection
GO:0045211  postsynaptic membrane

Molecular Function

GO:0005543  phospholipid binding