forkhead box F2

 jump to detail

Synonym

forkhead box F2, Forkhead-related protein FKHL6, Forkhead-related transcription factor 2, Forkhead-related activator 2, FOXF2, FKHL6, Forkhead box protein F2, FREAC2, FREAC-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:38.40
GeneChip cerebrum:4.93 cerebellum:4.55 brain stem:4.88 corpus callosum/glia:4.87 pineal gland:- peripheral nerve:4.24 spine:4.91 retina:- eye:- artery/aorta:4.45 vein:4.46 lymphnode:4.53 peripheral blood:- spleen:3.64 thymus:3.63 bone marrow:4.17 adipose:4.58 bone:- skin:4.74
CAGE cerebrum:1.47 cerebellum:- brain stem:1.50 corpus callosum/glia:1.66 pineal gland:1.23 peripheral nerve:- spine:1.28 retina:- eye:- artery/aorta:1.22 vein:0 lymphnode:1.04 peripheral blood:- spleen:0.09 thymus:0.06 bone marrow:- adipose:0.84 bone:- skin:-
RNA-seq cerebrum:0.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.09 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:9.80    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.93 placenta:6.18 prostate:4.60 ovary:3.77 testis:3.90 heart:4.11 muscle:4.29 esophagus:5.87 stomach:7.46 intestine:6.54 colon:7.60 liver/hepato:3.95 lung:6.56 bladder:- kidney:3.75 pituitary:5.07 thyroid/parathyroid:4.42 adrenal gland:4.03 pancreas:4.20 breast:4.70 salivary:4.10
CAGE uterus:0.91 placenta:2.45 prostate:3.23 ovary:0.20 testis:0.55 heart:0.21 muscle:0.42 esophagus:3.90 stomach:- intestine:3.34 colon:3.90     liver/hepato:0.46    lung:3.18 bladder:2.86 kidney:0.27 pituitary:1.15 thyroid/parathyroid:1.35 adrenal gland:- pancreas:0 breast:1.68 salivary:0
RNA-seq uterus:- placenta:- prostate:2.11 ovary:0.24 testis:1.25 heart:0.17 muscle:0.26 esophagus:- stomach:- intestine:- colon:4.53     liver/hepato:0.00        lung:3.06    bladder:- kidney:0.40 pituitary:- thyroid/parathyroid:0.76 adrenal gland:0.52 pancreas:- breast:0.60 salivary:-

Gene Information

IDs

Refseq ID NM_001452
Gene ID 2295
Unigene ID Hs.484423
Probe set ID 206377_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137273
GTEx ID ENSG00000137273

Orthologous Gene

Mouse[1]  NM_010225
Rat[1]  NM_010225

Chromosomal Region

6p25.3  [1,390,069  -  1,395,832]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

7957066
7959731
8626802
9722567
9799607
17474147
19220249
19276632
19562724
20634891
23383207
23620774

Gene Ontology  (GO ID)

Biological Process

GO:0048596  embryonic camera-type eye morphogenesis
GO:0009790  embryonic development
GO:0048566  embryonic gut development
GO:0001837  epithelial to mesenchymal transition
GO:0042249  establishment of planar polarity of embryonic epithelium
GO:0030198  extracellular matrix organization
GO:0048806  genitalia development
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0060021  palate development
GO:0007389  pattern specification process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0051090  regulation of transcription factor activity
GO:0009888  tissue development

Cellular Component

GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0003690  double-stranded DNA binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding