tripartite motif-containing 32

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Synonym

Tripartite motif-containing protein 32, LGMD2H, HT2A, 72 kDa Tat-interacting protein, TATIP, BBS11, TRIM32, Zinc finger protein HT2A, tripartite motif-containing 32

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:37.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:24
GeneChip cerebrum:6.08 cerebellum:7.36 brain stem:6.08 corpus callosum/glia:5.69 pineal gland:- peripheral nerve:6.17 spine:5.97 retina:- eye:- artery/aorta:6.23 vein:6.17 lymphnode:6.09 peripheral blood:- spleen:6.34 thymus:6.08 bone marrow:5.36 adipose:6.15 bone:- skin:6.05
CAGE cerebrum:2.17 cerebellum:- brain stem:1.94 corpus callosum/glia:2.10 pineal gland:2.17 peripheral nerve:- spine:1.32 retina:- eye:- artery/aorta:2.48 vein:2.09 lymphnode:1.77 peripheral blood:- spleen:1.91 thymus:2.17 bone marrow:- adipose:2.33 bone:- skin:-
RNA-seq cerebrum:1.46 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.50 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:40.10 prostate:56.30 ovary:37.30 testis:13 heart:63.90 muscle:- esophagus:- stomach:63.70 intestine:- colon:42.40     liver/hepato:-        lung:48.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:6.94 placenta:5.80 prostate:6.17 ovary:6.91 testis:6.19 heart:6.04 muscle:7.15 esophagus:6.27 stomach:6.12 intestine:6.18 colon:6.39 liver/hepato:5.59 lung:5.79 bladder:- kidney:5.93 pituitary:6.07 thyroid/parathyroid:6.26 adrenal gland:6.07 pancreas:6.09 breast:6.47 salivary:6
CAGE uterus:2.72 placenta:1.84 prostate:2.44 ovary:2.43 testis:2.18 heart:2.09 muscle:2.55 esophagus:2.12 stomach:- intestine:2.23 colon:2.25     liver/hepato:1.60    lung:1.87 bladder:1.96 kidney:1.81 pituitary:2.05 thyroid/parathyroid:2.16 adrenal gland:- pancreas:2.48 breast:2.11 salivary:2.50
RNA-seq uterus:- placenta:- prostate:2.36 ovary:1.63 testis:2.48 heart:1.21 muscle:3.14 esophagus:- stomach:- intestine:- colon:1.67     liver/hepato:0.83        lung:1.73    bladder:- kidney:2.14 pituitary:- thyroid/parathyroid:1.17 adrenal gland:0.00 pancreas:- breast:1.59 salivary:-

Gene Information

IDs

Refseq ID NM_001099679
Gene ID 22954
Unigene ID Hs.591910
Probe set ID 203846_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000119401
GTEx ID ENSG00000119401

Orthologous Gene

Mouse[2]  NM_001161782, NM_053084
Rat [0]  

Chromosomal Region

9q33.1  [119,449,581  -  119,463,579]

Gene Family (Interpro ID)

IPR001258  NHL repeat
IPR013017  NHL repeat, subgroup
IPR000315  Zinc finger, B-box

Link to Pubmed  (Pubmed ID)

7778269
9634523
11331580
11822024
12477932
12549820
15164053
15489334
15778465
15786463
16175175
16189514
16606853
16713569
16816390
17987106
17994549
18248090
18632609
18781797
19060904
19303295
19349376
19492423
19549727
19690564
19913121
20054338
20301537
20301582
20301743
20628086
20801516
21139048
21143188
21415862
21496629
21628460
21798009
21890473
21903422
21906983
21963094
21984809
21987572
22182411
22493164
22745133
22797925
22939624
23000965
23022380
23408431
23444366
23828567
24250222
24255178
24500717
24778252
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0045444  fat cell differentiation
GO:0045087  innate immune response
GO:0048147  negative regulation of fibroblast proliferation
GO:0045787  positive regulation of cell cycle
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0050769  positive regulation of neurogenesis
GO:0045666  positive regulation of neuron differentiation
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045732  positive regulation of protein catabolic process
GO:0045862  positive regulation of proteolysis
GO:0032481  positive regulation of type I interferon production
GO:0000209  protein polyubiquitination
GO:0016567  protein ubiquitination
GO:0042787  protein ubiquitination during ubiquitin-dependent protein catabolic process
GO:0032479  regulation of type I interferon production
GO:0034612  response to tumor necrosis factor
GO:0009411  response to UV

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus
GO:0005863  striated muscle thick filament

Molecular Function

GO:0017022  myosin binding
GO:0005515  protein binding
GO:0043621  protein self-association
GO:0003723  RNA binding
GO:0030957  Tat protein binding
GO:0003713  transcription coactivator activity
GO:0031369  translation initiation factor binding
GO:0043130  ubiquitin binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding