forkhead box D4

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Synonym

Forkhead-related protein FKHL9, Forkhead box protein D4, Myeloid factor-alpha, forkhead box D4, FOXD4A, FKHL9, FOXD4a, Forkhead-related transcription factor 5, MGC105106, FREAC5, FOXD4, FREAC-5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.64 cerebellum:3.67 brain stem:3.75 corpus callosum/glia:3.45 pineal gland:- peripheral nerve:3.17 spine:3.25 retina:- eye:- artery/aorta:3.38 vein:3.57 lymphnode:3.51 peripheral blood:- spleen:3.17 thymus:3.14 bone marrow:3.48 adipose:3.41 bone:- skin:3.32
CAGE nodata
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.55 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.05 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.39 placenta:3.41 prostate:3.29 ovary:3.54 testis:3.24 heart:3.65 muscle:3.78 esophagus:3.40 stomach:3.39 intestine:3.43 colon:3.61 liver/hepato:3.52 lung:3.43 bladder:- kidney:3.48 pituitary:3.42 thyroid/parathyroid:3.29 adrenal gland:3.48 pancreas:3.55 breast:3.33 salivary:3.61
CAGE nodata
RNA-seq uterus:- placenta:- prostate:0.20 ovary:0.24 testis:0.16 heart:0.01 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.06     liver/hepato:0.08        lung:0.18    bladder:- kidney:0.21 pituitary:- thyroid/parathyroid:0.13 adrenal gland:0.10 pancreas:- breast:0.05 salivary:-

Gene Information

IDs

Refseq ID NM_207305
Gene ID 2298
Unigene ID Hs.584759
Probe set ID 217032_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170122
GTEx ID ENSG00000170122

Orthologous Gene

Mouse[1]  NM_008022
Rat[1]  NM_008022

Chromosomal Region

9p24.3  [116,237  -  118,417]

Gene Family (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

7957066
8825632
8889548
9325056
12234674
12421752
12477932
15164053
15233989
15489334
15492844
17273782
18029348
20650821
21482378
21948691
22876580

Gene Ontology  (GO ID)

Biological Process

GO:0048846  axon extension involved in axon guidance
GO:0051216  cartilage development
GO:0060678  dichotomous subdivision of terminal units involved in ureteric bud branching
GO:0009790  embryonic development
GO:0048484  enteric nervous system development
GO:0050935  iridophore differentiation
GO:0048937  lateral line nerve glial cell development
GO:0030318  melanocyte differentiation
GO:0007275  multicellular organismal development
GO:0001755  neural crest cell migration
GO:0007389  pattern specification process
GO:0007422  peripheral nervous system development
GO:0030513  positive regulation of BMP signaling pathway
GO:0090184  positive regulation of kidney development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051090  regulation of transcription factor activity
GO:0006355  regulation of transcription, DNA-dependent
GO:0048485  sympathetic nervous system development

Cellular Component

GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0008301  DNA bending activity
GO:0003690  double-stranded DNA binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding