Fas apoptotic inhibitory molecule 2

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Synonym

KIAA0950, NMP35, Lifeguard protein, FAIM2, Fas apoptotic inhibitory molecule 2, TMBIM2, LFG, NGP35, LIFEGUARD

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:263.10 cerebellum:327.40 brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:30.70 spine:224.60 retina:118.60 eye:129.30 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:8.95 cerebellum:8.56 brain stem:9.19 corpus callosum/glia:8.44 pineal gland:- peripheral nerve:9.35 spine:8.76 retina:- eye:- artery/aorta:5.76 vein:5.54 lymphnode:4.94 peripheral blood:- spleen:4.22 thymus:4.06 bone marrow:4.60 adipose:4.76 bone:- skin:4.75
CAGE cerebrum:6.18 cerebellum:- brain stem:6.26 corpus callosum/glia:6.10 pineal gland:2.86 peripheral nerve:- spine:5.33 retina:- eye:- artery/aorta:2.00 vein:2.39 lymphnode:1.33 peripheral blood:- spleen:1.06 thymus:1.31 bone marrow:- adipose:1.66 bone:- skin:-
RNA-seq cerebrum:6.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.47 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.34 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:37.30 testis:8.70 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:42.40     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:9.30 salivary:-
GeneChip uterus:5.12 placenta:4.17 prostate:5.28 ovary:4.84 testis:7.23 heart:5.35 muscle:4.44 esophagus:4.79 stomach:4.98 intestine:5.02 colon:5.33 liver/hepato:4.28 lung:4.57 bladder:- kidney:4.53 pituitary:7.82 thyroid/parathyroid:4.48 adrenal gland:5.64 pancreas:5.21 breast:4.88 salivary:4.88
CAGE uterus:2.44 placenta:0.43 prostate:3.69 ovary:3.04 testis:3.92 heart:2.83 muscle:0.21 esophagus:1.92 stomach:- intestine:1.96 colon:2.16     liver/hepato:0.26    lung:1.16 bladder:2.67 kidney:1.26 pituitary:3.93 thyroid/parathyroid:1.07 adrenal gland:- pancreas:0.94 breast:1.68 salivary:0.83
RNA-seq uterus:- placenta:- prostate:2.00 ovary:2.44 testis:2.45 heart:0.96 muscle:0.01 esophagus:- stomach:- intestine:- colon:2.04     liver/hepato:0.01        lung:0.36    bladder:- kidney:0.38 pituitary:- thyroid/parathyroid:1.14 adrenal gland:1.16 pancreas:- breast:0.80 salivary:-

Gene Information

IDs

Refseq ID NM_012306
Gene ID 23017
Unigene ID Hs.567424
Probe set ID 203619_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135472
GTEx ID ENSG00000135472

Orthologous Gene

Mouse[2]  NM_001038658, NM_028224
Rat [0]  

Chromosomal Region

12q13.12  [50,260,679  -  50,298,000]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10231032
10535980
12477932
14702039
15489334
16964429
17207965
17635665
17912957
18440869
19079260
19557197
19812171
19851340
20215397
20336406
20816195
20843981
20935630
21935397
21957071
22889921
23924573
24335530

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0021681  cerebellar granular layer development
GO:0021702  cerebellar Purkinje cell differentiation
GO:0021680  cerebellar Purkinje cell layer development
GO:0021549  cerebellum development
GO:0043066  negative regulation of apoptosis
GO:0043523  regulation of neuron apoptosis

Cellular Component

GO:0030054  cell junction
GO:0005575  cellular_component
GO:0016021  integral to membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane