sterile alpha motif domain containing 4A

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Synonym

SMGA, sterile alpha motif domain containing 4A, KIAA1053, DKFZp434H0350, Smaug1, sterile alpha motif domain containing 4, SAMD4A, DKFZP434H0350, Sterile alpha motif domain-containing protein 4, SMG, SAMD4, Smaug

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:72.30 cerebellum:75.60 brain stem:6535.90 corpus callosum/glia:29.20 pineal gland:- peripheral nerve:276 spine:- retina:118.60 eye:35.30 artery/aorta:60 vein:- lymphnode:10.10 peripheral blood:- spleen:75.60 thymus:12.90 bone marrow:19.70 adipose:201.70 bone:38.40 skin:62.40
GeneChip cerebrum:7.96 cerebellum:8.55 brain stem:8.60 corpus callosum/glia:8.84 pineal gland:- peripheral nerve:7.30 spine:9.86 retina:- eye:- artery/aorta:8.70 vein:9.09 lymphnode:6.69 peripheral blood:- spleen:7.39 thymus:5.57 bone marrow:5.40 adipose:7.99 bone:- skin:7.35
CAGE cerebrum:2.29 cerebellum:- brain stem:2.53 corpus callosum/glia:2.61 pineal gland:1.91 peripheral nerve:- spine:3.19 retina:- eye:- artery/aorta:3.31 vein:2.09 lymphnode:1.91 peripheral blood:- spleen:1.72 thymus:0.83 bone marrow:- adipose:1.99 bone:- skin:-
RNA-seq cerebrum:1.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.21 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.55 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:127.60 placenta:109.30 prostate:45.10 ovary:- testis:302.90 heart:114.90 muscle:160.70 esophagus:342.80 stomach:- intestine:32.40 colon:127.20     liver/hepato:52.80        lung:92.90    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:167.30 salivary:-
GeneChip uterus:8.24 placenta:7.24 prostate:7.66 ovary:7.14 testis:5.65 heart:9.19 muscle:10.07 esophagus:7.33 stomach:7.45 intestine:7.79 colon:7.59 liver/hepato:8.19 lung:7.42 bladder:- kidney:6.59 pituitary:6.41 thyroid/parathyroid:6.50 adrenal gland:6.79 pancreas:6.35 breast:7.66 salivary:5.90
CAGE uterus:2.85 placenta:1.95 prostate:2.61 ovary:1.53 testis:4.89 heart:2.97 muscle:3.26 esophagus:2.28 stomach:- intestine:1.77 colon:2.33     liver/hepato:2.19    lung:1.99 bladder:3.25 kidney:1.09 pituitary:1.29 thyroid/parathyroid:1.35 adrenal gland:- pancreas:0.94 breast:0.90 salivary:1.28
RNA-seq uterus:- placenta:- prostate:1.63 ovary:0.46 testis:3.70 heart:3.82 muscle:3.89 esophagus:- stomach:- intestine:- colon:1.36     liver/hepato:0.46        lung:2.91    bladder:- kidney:0.26 pituitary:- thyroid/parathyroid:2.86 adrenal gland:1.29 pancreas:- breast:2.94 salivary:-

Gene Information

IDs

Refseq ID NM_015589
Gene ID 23034
Unigene ID Hs.98259
Probe set ID 212845_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000020577
GTEx ID ENSG00000020577

Orthologous Gene

Mouse[3]  NM_001037221, NM_001163433, NM_028966
Rat[1]  NM_001107254, NM_001163433, NM_028966

Chromosomal Region

14q22.2  [55,033,815  -  55,260,033]

Gene Family (Interpro ID)

IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type

Link to Pubmed  (Pubmed ID)

10470851
12477932
15324660
16221671
16344560
19913121
20379614
20628086
22201125
23251661
24023788
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0017148  negative regulation of translation
GO:0045727  positive regulation of translation

Cellular Component

GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0045202  synapse

Molecular Function

GO:0030371  translation repressor activity