plexin D1

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Synonym

KIAA0620, PLXND1, plexin D1, PLEXD1, Plexin-D1 precursor, MGC75353

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:33.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:184 spine:- retina:- eye:41.10 artery/aorta:- vein:66.60 lymphnode:10.10 peripheral blood:36.40 spleen:56.70 thymus:38.70 bone marrow:118.10 adipose:80.70 bone:25.60 skin:43.20
GeneChip cerebrum:7.55 cerebellum:6.66 brain stem:7.62 corpus callosum/glia:8.03 pineal gland:- peripheral nerve:8.63 spine:8.02 retina:- eye:- artery/aorta:8.36 vein:7.98 lymphnode:8.38 peripheral blood:- spleen:8.40 thymus:8.16 bone marrow:7.66 adipose:8.82 bone:- skin:7.86
CAGE cerebrum:3.05 cerebellum:- brain stem:3.90 corpus callosum/glia:3.96 pineal gland:3.12 peripheral nerve:- spine:3.94 retina:- eye:- artery/aorta:4.35 vein:4.54 lymphnode:4.04 peripheral blood:- spleen:4.11 thymus:4.18 bone marrow:- adipose:4.44 bone:- skin:-
RNA-seq cerebrum:2.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.09 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:69.20 prostate:56.30 ovary:- testis:21.60 heart:166 muscle:- esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:10.60        lung:48.90    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:102.20 salivary:-
GeneChip uterus:8.34 placenta:8.45 prostate:7.14 ovary:7.61 testis:6.96 heart:7.99 muscle:6.87 esophagus:7.41 stomach:7.86 intestine:7.67 colon:7.60 liver/hepato:7.68 lung:9.01 bladder:- kidney:7.52 pituitary:7.19 thyroid/parathyroid:7.92 adrenal gland:8.35 pancreas:6.76 breast:8.31 salivary:6.74
CAGE uterus:4.23 placenta:4.52 prostate:3.58 ovary:3.41 testis:3.09 heart:4.22 muscle:3.19 esophagus:3.11 stomach:- intestine:2.94 colon:3.51     liver/hepato:3.54    lung:4.47 bladder:3.45 kidney:3.48 pituitary:2.01 thyroid/parathyroid:3.03 adrenal gland:- pancreas:3.13 breast:5.00 salivary:2.35
RNA-seq uterus:- placenta:- prostate:3.02 ovary:3.21 testis:3.16 heart:2.54 muscle:1.52 esophagus:- stomach:- intestine:- colon:2.67     liver/hepato:2.22        lung:3.79    bladder:- kidney:2.88 pituitary:- thyroid/parathyroid:3.12 adrenal gland:4.71 pancreas:- breast:4.45 salivary:-

Gene Information

IDs

Refseq ID NM_015103
Gene ID 23129
Unigene ID Hs.301685
Probe set ID 38671_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000004399
GTEx ID ENSG00000004399

Orthologous Gene

Mouse[1]  NM_026376
Rat[1]  NM_026376

Chromosomal Region

3q22.1  [129,274,018  -  129,325,661]

Gene Family (Interpro ID)

IPR002909  Cell surface receptor IPT/TIG
IPR014756  Immunoglobulin E-set
IPR003659  Plexin/semaphorin/integrin
IPR001627  Semaphorin/CD100 antigen
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

9734811
10520995
12412018
12421765
12477932
15239958
15301830
15489334
15550623
16335952
17318185
18974298
19703316
20385769
20664171
21139048
21505259
21559368
21795701
22738647
24139859
24254849

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0007411  axon guidance
GO:0060666  dichotomous subdivision of terminal units involved in salivary gland branching
GO:0043542  endothelial cell migration
GO:0001569  patterning of blood vessels
GO:0045765  regulation of angiogenesis
GO:0030334  regulation of cell migration
GO:0007416  synapse assembly

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005622  intracellular
GO:0005886  plasma membrane

Molecular Function

GO:0017154  semaphorin receptor activity