mitogen-activated protein kinase 8 interacting protein 3

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Synonym

SYD2, KIAA1066, JNK MAP kinase scaffold protein 3, JNK-interacting protein 3, FLJ00027, JIP-3, C-jun-amino-terminal kinase-interacting protein 3, MAPK8IP3, JSAP1, DKFZp762N1113, JIP3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:61.30 spine:224.60 retina:- eye:152.80 artery/aorta:- vein:- lymphnode:262.90 peripheral blood:36.40 spleen:56.70 thymus:38.70 bone marrow:157.40 adipose:- bone:76.80 skin:28.80
GeneChip cerebrum:5.09 cerebellum:5.39 brain stem:5.04 corpus callosum/glia:5.17 pineal gland:- peripheral nerve:4.77 spine:5.05 retina:- eye:- artery/aorta:4.93 vein:4.97 lymphnode:4.77 peripheral blood:- spleen:4.55 thymus:4.90 bone marrow:5.08 adipose:4.99 bone:- skin:4.98
CAGE cerebrum:4.93 cerebellum:- brain stem:4.79 corpus callosum/glia:4.78 pineal gland:4.74 peripheral nerve:- spine:4.33 retina:- eye:- artery/aorta:3.33 vein:3.43 lymphnode:3.08 peripheral blood:- spleen:2.84 thymus:2.98 bone marrow:- adipose:2.93 bone:- skin:-
RNA-seq cerebrum:3.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.59 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.90 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:43.70 prostate:11.30 ovary:37.30 testis:30.30 heart:12.80 muscle:20.10 esophagus:- stomach:42.50 intestine:- colon:186.60     liver/hepato:-        lung:83.10    bladder:- kidney:93.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:37.20 salivary:-
GeneChip uterus:4.85 placenta:4.87 prostate:4.63 ovary:4.98 testis:4.76 heart:4.91 muscle:4.94 esophagus:5.01 stomach:4.55 intestine:4.79 colon:4.82 liver/hepato:4.85 lung:4.75 bladder:- kidney:4.81 pituitary:4.98 thyroid/parathyroid:4.67 adrenal gland:4.55 pancreas:5.18 breast:4.56 salivary:4.90
CAGE uterus:3.23 placenta:2.64 prostate:3.10 ovary:2.76 testis:2.88 heart:3.41 muscle:3.38 esophagus:2.43 stomach:- intestine:2.78 colon:2.95     liver/hepato:1.54    lung:2.82 bladder:3.47 kidney:2.23 pituitary:4.13 thyroid/parathyroid:2.43 adrenal gland:- pancreas:2.98 breast:2.53 salivary:3.17
RNA-seq uterus:- placenta:- prostate:2.56 ovary:2.45 testis:2.57 heart:1.96 muscle:1.02 esophagus:- stomach:- intestine:- colon:1.32     liver/hepato:0.73        lung:2.50    bladder:- kidney:1.62 pituitary:- thyroid/parathyroid:2.29 adrenal gland:3.18 pancreas:- breast:1.74 salivary:-

Gene Information

IDs

Refseq ID NM_001040439
Gene ID 23162
Unigene ID Hs.207763
Probe set ID 216139_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000138834
GTEx ID ENSG00000138834

Orthologous Gene

Mouse[28]  NM_001163447, NM_001163448, NM_001163449, NM_001163450, NM_001163451, NM_001163453, NM_013931
Rat[1]  NM_001100673, NM_001163448, NM_001163449, NM_001163450, NM_001163451, NM_001163453, NM_013931

Chromosomal Region

16p13.3  [1,756,194  -  1,820,318]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10470851
10523642
10629060
11024282
11044439
11106729
11157797
11214971
11274738
11738026
12189133
12226752
12477932
12941697
14702039
14968112
15146197
15258908
15302935
15532711
15616553
15911620
16141199
16147992
16169070
16341674
16368877
16456539
19036714
19574423
20018857
20173330
20946988
21697133
21775604
22072677

Gene Ontology  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0007411  axon guidance
GO:0030900  forebrain development
GO:0001701  in utero embryonic development
GO:0048286  lung alveolus development
GO:0060425  lung morphogenesis
GO:0009791  post-embryonic development
GO:0008104  protein localization
GO:0010468  regulation of gene expression
GO:0046328  regulation of JNK cascade
GO:0007585  respiratory gaseous exchange
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0030673  axolemma
GO:0030425  dendrite
GO:0000139  Golgi membrane
GO:0005790  smooth endoplasmic reticulum

Molecular Function

GO:0008432  JUN kinase binding
GO:0019894  kinesin binding
GO:0005078  MAP-kinase scaffold activity
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0019901  protein kinase binding