methionyl aminopeptidase 1

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Synonym

DKFZp781C0419, METAP1, Methionine aminopeptidase 1, KIAA0094, Peptidase M 1, MetAP 1, methionyl aminopeptidase 1, MAP 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:29.60 cerebellum:- brain stem:- corpus callosum/glia:233.30 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:29.40 artery/aorta:239.80 vein:66.60 lymphnode:91 peripheral blood:- spleen:18.90 thymus:154.60 bone marrow:- adipose:40.30 bone:- skin:100.80
GeneChip cerebrum:6.51 cerebellum:6.25 brain stem:6.34 corpus callosum/glia:6.26 pineal gland:- peripheral nerve:6.59 spine:6.36 retina:- eye:- artery/aorta:7.43 vein:7.30 lymphnode:7.25 peripheral blood:- spleen:7.12 thymus:8.22 bone marrow:6.89 adipose:6.94 bone:- skin:7.24
CAGE cerebrum:3.46 cerebellum:- brain stem:3.29 corpus callosum/glia:3.13 pineal gland:3.83 peripheral nerve:- spine:3.67 retina:- eye:- artery/aorta:4.33 vein:3.72 lymphnode:3.77 peripheral blood:- spleen:3.70 thymus:4.13 bone marrow:- adipose:3.44 bone:- skin:-
RNA-seq cerebrum:3.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.13 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.44 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:29.10 prostate:- ovary:37.30 testis:212 heart:63.90 muscle:60.30 esophagus:342.80 stomach:85 intestine:97.20 colon:42.40     liver/hepato:21.10        lung:44    bladder:125.60 kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:92.90 salivary:-
GeneChip uterus:7.62 placenta:6.37 prostate:8.21 ovary:7.27 testis:7.26 heart:7.38 muscle:7.53 esophagus:7.98 stomach:6.94 intestine:7.17 colon:7.25 liver/hepato:6.81 lung:6.85 bladder:- kidney:7.06 pituitary:6.86 thyroid/parathyroid:7.21 adrenal gland:6.25 pancreas:6.79 breast:7.45 salivary:7.10
CAGE uterus:3.93 placenta:3.20 prostate:4.06 ovary:3.51 testis:4.13 heart:4.12 muscle:3.84 esophagus:4.37 stomach:- intestine:3.78 colon:4.11     liver/hepato:3.54    lung:3.59 bladder:4.38 kidney:3.71 pituitary:3.79 thyroid/parathyroid:3.43 adrenal gland:- pancreas:3.57 breast:4.04 salivary:3.85
RNA-seq uterus:- placenta:- prostate:5.16 ovary:4.00 testis:4.80 heart:4.47 muscle:4.02 esophagus:- stomach:- intestine:- colon:4.21     liver/hepato:3.18        lung:3.53    bladder:- kidney:4.06 pituitary:- thyroid/parathyroid:3.80 adrenal gland:4.22 pancreas:- breast:3.72 salivary:-

Gene Information

IDs

Refseq ID NM_015143
Gene ID 23173
Unigene ID Hs.480364
Probe set ID 212673_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164024
GTEx ID ENSG00000164024

Orthologous Gene

Mouse[3]  NM_175224
Rat[1]  NM_001106476

Chromosomal Region

4q23  [99,916,771  -  99,983,964]

Gene Family (Interpro ID)

IPR001714  Peptidase M24, methionine aminopeptidase
IPR002467  Peptidase M24A, methionine aminopeptidase, subfamily 1

Link to Pubmed  (Pubmed ID)

7788527
12144506
12477932
14532271
15231748
15489334
15592455
15635413
16274222
16344560
16386852
17114291
17353931
17929833
19898482
20379614
20521764
21139048
21906983
21963094
23767698
24163370
24654937

Gene Ontology  (GO ID)

Biological Process

GO:0031365  N-terminal protein amino acid modification
GO:0018206  peptidyl-methionine modification
GO:0007603  phototransduction, visible light
GO:0006508  proteolysis
GO:0022400  regulation of rhodopsin mediated signaling pathway
GO:0006417  regulation of translation
GO:0016056  rhodopsin mediated signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol

Molecular Function

GO:0004177  aminopeptidase activity
GO:0046872  metal ion binding
GO:0008235  metalloexopeptidase activity