jumonji domain containing 6

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Synonym

Phosphatidylserine receptor, PTDSR, PTDSR1, Protein PTDSR, PSR, phosphatidylserine receptor, KIAA0585

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:42.70 cerebellum:37.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:355.90 eye:76.40 artery/aorta:89.90 vein:66.60 lymphnode:50.60 peripheral blood:145.70 spleen:37.80 thymus:12.90 bone marrow:19.70 adipose:80.70 bone:64 skin:14.40
GeneChip cerebrum:5.68 cerebellum:5.11 brain stem:5.88 corpus callosum/glia:6.27 pineal gland:- peripheral nerve:6.45 spine:6.20 retina:- eye:- artery/aorta:7.72 vein:7.99 lymphnode:7.21 peripheral blood:- spleen:7.42 thymus:6.83 bone marrow:7.66 adipose:6.69 bone:- skin:6.81
CAGE cerebrum:2.97 cerebellum:- brain stem:3.10 corpus callosum/glia:2.78 pineal gland:3.04 peripheral nerve:- spine:3.16 retina:- eye:- artery/aorta:3.34 vein:2.90 lymphnode:2.48 peripheral blood:- spleen:2.77 thymus:2.19 bone marrow:- adipose:2.95 bone:- skin:-
RNA-seq cerebrum:1.96 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.16 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.98 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:54.60 prostate:123.90 ovary:223.60 testis:60.60 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:97.20 colon:59.40     liver/hepato:63.30        lung:39.10    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:101.60 pancreas:88.90 breast:- salivary:-
GeneChip uterus:6.76 placenta:6.56 prostate:7.06 ovary:6.82 testis:7.69 heart:7.07 muscle:6.19 esophagus:6.95 stomach:7.04 intestine:6.86 colon:6.46 liver/hepato:6.68 lung:8.05 bladder:- kidney:6.71 pituitary:6.67 thyroid/parathyroid:6.78 adrenal gland:7.65 pancreas:6.39 breast:6.83 salivary:6.77
CAGE uterus:2.67 placenta:2.58 prostate:3.10 ovary:2.95 testis:3.39 heart:3.46 muscle:3.38 esophagus:3.07 stomach:- intestine:2.84 colon:2.82     liver/hepato:2.33    lung:2.92 bladder:3.38 kidney:2.46 pituitary:3.17 thyroid/parathyroid:2.91 adrenal gland:- pancreas:2.76 breast:3.38 salivary:2.57
RNA-seq uterus:- placenta:- prostate:3.99 ovary:3.07 testis:3.61 heart:2.08 muscle:1.42 esophagus:- stomach:- intestine:- colon:4.14     liver/hepato:2.24        lung:4.58    bladder:- kidney:2.97 pituitary:- thyroid/parathyroid:2.67 adrenal gland:2.78 pancreas:- breast:2.24 salivary:-

Gene Information

IDs

Refseq ID NM_015167
Gene ID 23210
Unigene ID Hs.514505
Probe set ID 212723_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000070495
GTEx ID ENSG00000070495

Orthologous Gene

Mouse[2]  NM_033398
Rat[2]  NM_033398

Chromosomal Region

17q25.1  [74,708,919  -  74,722,866]

Gene Family (Interpro ID)

IPR003347  Transcription factor jumonji/aspartyl beta-hydroxylase

Link to Pubmed  (Pubmed ID)

9628581
10811223
11877474
12477932
12559004
12898702
14645848
14702039
14729065
15072554
15193161
15345036
15453906
15469976
15489334
15622002
16983801
17534701
17947579
18564434
19492415
19574390
20574068
20679243
20684070
21139048
21300889
21890473
21906983
21963094
22189873
22505724
22621393
22701020
22863883
23303181
23455924
23595221
23688307
23776548
24360279
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007166  cell surface receptor linked signal transduction
GO:0048821  erythrocyte development
GO:0007507  heart development
GO:0070078  histone H3-R2 demethylation
GO:0070079  histone H4-R3 demethylation
GO:0001822  kidney development
GO:0030324  lung development
GO:0042116  macrophage activation
GO:0006397  mRNA processing
GO:0018395  peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
GO:0043654  recognition of apoptotic cell
GO:0048024  regulation of nuclear mRNA splicing, via spliceosome
GO:0006355  regulation of transcription, DNA-dependent
GO:0060041  retina development in camera-type eye
GO:0008380  RNA splicing
GO:0002040  sprouting angiogenesis
GO:0033077  T cell differentiation in the thymus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0033746  histone demethylase activity (H3-R2 specific)
GO:0033749  histone demethylase activity (H4-R3 specific)
GO:0042802  identical protein binding
GO:0005506  iron ion binding
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0070815  peptidyl-lysine 5-dioxygenase activity
GO:0005515  protein binding
GO:0004872  receptor activity
GO:0003723  RNA binding
GO:0003727  single-stranded RNA binding