acyl-CoA synthetase long-chain family member 6

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Synonym

FACL6, ACSL6, LACS5, acyl-CoA synthetase long-chain family member 6, Long-chain acyl-CoA synthetase 6, ACS2, LACS 6, LACS2, Long-chain-fatty-acid--CoA ligase 6, KIAA0837

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:5.90 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.88 cerebellum:5.86 brain stem:4.97 corpus callosum/glia:4.03 pineal gland:- peripheral nerve:4.86 spine:4.67 retina:- eye:- artery/aorta:3.45 vein:3.64 lymphnode:3.50 peripheral blood:- spleen:3.35 thymus:3.37 bone marrow:4.54 adipose:3.46 bone:- skin:3.34
CAGE cerebrum:3.47 cerebellum:- brain stem:2.99 corpus callosum/glia:2.91 pineal gland:3.21 peripheral nerve:- spine:2.70 retina:- eye:- artery/aorta:0.59 vein:1.34 lymphnode:2.18 peripheral blood:- spleen:1.09 thymus:0.61 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:3.34 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.85 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.27 placenta:3.22 prostate:3.17 ovary:3.20 testis:3.62 heart:3.55 muscle:3.64 esophagus:3.27 stomach:3.40 intestine:3.57 colon:3.43 liver/hepato:3.43 lung:3.34 bladder:- kidney:3.55 pituitary:3.81 thyroid/parathyroid:3.31 adrenal gland:3.77 pancreas:3.42 breast:3.27 salivary:3.42
CAGE uterus:0.21 placenta:0.24 prostate:0.49 ovary:0.14 testis:2.18 heart:0.54 muscle:0.17 esophagus:0.46 stomach:- intestine:1.94 colon:1.07     liver/hepato:0.26    lung:0.69 bladder:0.78 kidney:1.09 pituitary:1.49 thyroid/parathyroid:0.41 adrenal gland:- pancreas:0 breast:0.55 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:2.28 heart:0.43 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.01        lung:0.02    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.02 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001009185
Gene ID 23305
Unigene ID Hs.149454
Probe set ID 213683_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164398
GTEx ID ENSG00000164398

Orthologous Gene

Mouse[4]  NM_001033597, NM_001033598, NM_001033599, NM_144823
Rat [0]  

Chromosomal Region

5q31.1  [131,142,683  -  131,347,936]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8944226
10048485
10502316
10548543
12477932
12767919
14702039
15292367
16344560
16572202
16806233
16827919
16834775
17030554
17567994
18555221
18718982
18804346
19064571
19460752
20379614
20429931
22205969
22412388
23128233

Gene Ontology  (GO ID)

Biological Process

GO:0006637  acyl-CoA metabolic process
GO:0044255  cellular lipid metabolic process
GO:0032869  cellular response to insulin stimulus
GO:0015908  fatty acid transport
GO:0001676  long-chain fatty acid metabolic process
GO:0007405  neuroblast proliferation
GO:0048666  neuron development
GO:0008654  phospholipid biosynthetic process
GO:0010976  positive regulation of neuron projection development
GO:0010747  positive regulation of plasma membrane long-chain fatty acid transport
GO:0010867  positive regulation of triglyceride biosynthetic process
GO:0009629  response to gravity
GO:0001666  response to hypoxia
GO:0007584  response to nutrient
GO:0048545  response to steroid hormone stimulus
GO:0019432  triglyceride biosynthetic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005741  mitochondrial outer membrane
GO:0005634  nucleus
GO:0005778  peroxisomal membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0019899  enzyme binding
GO:0004467  long-chain-fatty-acid-CoA ligase activity
GO:0042803  protein homodimerization activity