dedicator of cytokinesis 9

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Synonym

DOCK9, KIAA1085, dedicator of cytokinesis 9, Cdc42 guanine nucleotide exchange factor zizimin 1, zizimin1, FLJ45601, FLJ16744, ZIZ1, KIAA1058, DKFZp686N04132, FLJ44528, FLJ45282, Dedicator of cytokinesis protein 9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:7.33 cerebellum:7.19 brain stem:7.47 corpus callosum/glia:8.08 pineal gland:- peripheral nerve:7.34 spine:7.39 retina:- eye:- artery/aorta:5.77 vein:5.69 lymphnode:6.40 peripheral blood:- spleen:5.37 thymus:6.57 bone marrow:3.59 adipose:7.07 bone:- skin:7.45
CAGE cerebrum:4.18 cerebellum:- brain stem:4.86 corpus callosum/glia:5.15 pineal gland:3.56 peripheral nerve:- spine:4.45 retina:- eye:- artery/aorta:3.46 vein:3.30 lymphnode:3.36 peripheral blood:- spleen:2.90 thymus:2.01 bone marrow:- adipose:5.05 bone:- skin:-
RNA-seq cerebrum:3.06 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.64 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.33 placenta:7.39 prostate:6.56 ovary:6.25 testis:5.41 heart:6.47 muscle:5.44 esophagus:7.69 stomach:5.86 intestine:5.78 colon:5.51 liver/hepato:4.71 lung:7.71 bladder:- kidney:5.27 pituitary:5.35 thyroid/parathyroid:7.06 adrenal gland:5.63 pancreas:4.52 breast:6.66 salivary:6.47
CAGE uterus:3.69 placenta:4.21 prostate:3.25 ovary:3.03 testis:2.75 heart:3.87 muscle:2.97 esophagus:3.73 stomach:- intestine:3.11 colon:3.15     liver/hepato:2.10    lung:4.27 bladder:3.29 kidney:3.49 pituitary:2.76 thyroid/parathyroid:3.57 adrenal gland:- pancreas:2.60 breast:4.46 salivary:3.78
RNA-seq uterus:- placenta:- prostate:2.73 ovary:2.55 testis:2.63 heart:2.35 muscle:0.78 esophagus:- stomach:- intestine:- colon:2.97     liver/hepato:1.78        lung:3.66    bladder:- kidney:2.58 pituitary:- thyroid/parathyroid:3.84 adrenal gland:3.29 pancreas:- breast:2.71 salivary:-

Gene Information

IDs

Refseq ID NM_015296
Gene ID 23348
Unigene ID Hs.596105
Probe set ID 212538_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000088387
GTEx ID ENSG00000088387

Orthologous Gene

Mouse[12]  NM_001081039, NM_001128307, NM_001128308, NM_134074
Rat[1]  NM_001105759, NM_001128307, NM_001128308, NM_134074

Chromosomal Region

13q32.3  [99,445,741  -  99,738,879]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8889548
10470851
11991713
12168954
12172552
12432077
12477932
14702039
15057823
15489334
16344560
17728666
17935486
18056264
18729074
19745154
19809089
19946888
20379614
21139048
21145461
22889411
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0007596  blood coagulation
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005575  cellular_component
GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0016020  membrane

Molecular Function

GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0017048  Rho GTPase binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity