ras homolog gene family, member Q

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Synonym

RHOQ, ARHQ, ras homolog gene family, member Q, Rho-related GTP-binding protein RhoQ, RASL7A, TC10, TC10A, Ras-related GTP-binding protein TC10

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.86 cerebellum:7.57 brain stem:9.23 corpus callosum/glia:9.01 pineal gland:- peripheral nerve:9.80 spine:9.31 retina:- eye:- artery/aorta:9.44 vein:9.99 lymphnode:8.77 peripheral blood:- spleen:9.09 thymus:7.48 bone marrow:7.68 adipose:9.85 bone:- skin:8.58
CAGE cerebrum:2.15 cerebellum:- brain stem:2.42 corpus callosum/glia:2.06 pineal gland:2.31 peripheral nerve:- spine:2.38 retina:- eye:- artery/aorta:1.97 vein:1.49 lymphnode:1.52 peripheral blood:- spleen:1.72 thymus:1.43 bone marrow:- adipose:1.93 bone:- skin:-
RNA-seq cerebrum:4.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.69 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.05 placenta:8.09 prostate:9.08 ovary:8.88 testis:6.95 heart:10.55 muscle:10.29 esophagus:8.58 stomach:8.77 intestine:8.87 colon:7.98 liver/hepato:7.74 lung:9.02 bladder:- kidney:8.53 pituitary:8.19 thyroid/parathyroid:9.07 adrenal gland:9 pancreas:8.55 breast:9.09 salivary:8.14
CAGE uterus:1.94 placenta:1.50 prostate:1.89 ovary:2.28 testis:1.48 heart:2.77 muscle:2.37 esophagus:1.75 stomach:- intestine:1.44 colon:1.13     liver/hepato:1.16    lung:1.87 bladder:2.19 kidney:1.94 pituitary:1.97 thyroid/parathyroid:2.25 adrenal gland:- pancreas:1.98 breast:1.92 salivary:1.39
RNA-seq uterus:- placenta:- prostate:5.94 ovary:4.74 testis:4.55 heart:6.57 muscle:5.49 esophagus:- stomach:- intestine:- colon:5.63     liver/hepato:2.94        lung:5.50    bladder:- kidney:4.71 pituitary:- thyroid/parathyroid:4.99 adrenal gland:4.56 pancreas:- breast:6.71 salivary:-

Gene Information

IDs

Refseq ID NM_012249
Gene ID 23433
Unigene ID -
Probe set ID 212119_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000119729
GTEx ID ENSG00000119729

Orthologous Gene

Mouse[1]  NM_145491
Rat[1]  NM_053522

Chromosomal Region

2p21  [46,768,945  -  46,810,260]

Gene Family (Interpro ID)

IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

2108320
10445846
10490598
10934474
10967094
11149925
11162552
11309621
11821390
12134073
12242347
12456725
12477932
12508121
12529401
12687004
12972548
14702039
15194684
15304341
15361624
15489334
15546864
16246732
16950130
18660489
19258391
19322201
20416077
21139048
21890473
23000965
24297911
24663214

Gene Ontology  (GO ID)

Biological Process

GO:0032869  cellular response to insulin stimulus
GO:0030866  cortical actin cytoskeleton organization
GO:0006184  GTP catabolic process
GO:0008286  insulin receptor signaling pathway
GO:0090005  negative regulation of establishment of protein localization in plasma membrane
GO:0051491  positive regulation of filopodium assembly
GO:0046326  positive regulation of glucose import
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032956  regulation of actin cytoskeleton organization
GO:0008360  regulation of cell shape
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005884  actin filament
GO:0005829  cytosol
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0032427  GBD domain binding
GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005522  profilin binding