ATP-binding cassette, sub-family B (MDR/TAP), member 9

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Synonym

hABCB9, EST122234, TAPL, ATP-binding cassette transporter 9, KIAA1520, TAP-like protein, ABCB9, ABC transporter 9 protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:84.10 cerebellum:239.30 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:35.30 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:64.40 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.67 cerebellum:5.69 brain stem:5.58 corpus callosum/glia:5.38 pineal gland:- peripheral nerve:5.68 spine:5.09 retina:- eye:- artery/aorta:4.80 vein:5.45 lymphnode:4.96 peripheral blood:- spleen:4.57 thymus:4.28 bone marrow:4.99 adipose:5.08 bone:- skin:4.48
CAGE cerebrum:2.56 cerebellum:- brain stem:2.55 corpus callosum/glia:2.21 pineal gland:1.77 peripheral nerve:- spine:1.83 retina:- eye:- artery/aorta:1.85 vein:1.61 lymphnode:1.60 peripheral blood:- spleen:1.36 thymus:1.46 bone marrow:- adipose:1.37 bone:- skin:-
RNA-seq cerebrum:1.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.81 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:- prostate:- ovary:37.30 testis:60.60 heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:-     liver/hepato:10.60        lung:9.80    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip uterus:4.70 placenta:4.94 prostate:4.24 ovary:4.85 testis:6.89 heart:5.17 muscle:4.97 esophagus:4.96 stomach:4.87 intestine:5.05 colon:5.17 liver/hepato:4.68 lung:4.78 bladder:- kidney:5.02 pituitary:5.20 thyroid/parathyroid:4.85 adrenal gland:4.86 pancreas:5.28 breast:4.85 salivary:5.18
CAGE uterus:1.70 placenta:1.20 prostate:1.51 ovary:1.85 testis:2.40 heart:1.62 muscle:1.40 esophagus:1.41 stomach:- intestine:1.41 colon:2.01     liver/hepato:1.66    lung:1.23 bladder:1.15 kidney:1.51 pituitary:2.00 thyroid/parathyroid:1.17 adrenal gland:- pancreas:1.74 breast:1.36 salivary:2.17
RNA-seq uterus:- placenta:- prostate:0.12 ovary:1.26 testis:1.97 heart:0.18 muscle:0 esophagus:- stomach:- intestine:- colon:0.10     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.49 pituitary:- thyroid/parathyroid:0.31 adrenal gland:0.66 pancreas:- breast:0.57 salivary:-

Gene Information

IDs

Refseq ID NM_019625
Gene ID 23457
Unigene ID Hs.511951
Probe set ID 214209_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000150967
GTEx ID ENSG00000150967

Orthologous Gene

Mouse[3]  NM_019875
Rat[1]  NM_022238

Chromosomal Region

12q24.31  [123,405,498  -  123,466,196]

Gene Family (Interpro ID)

IPR017940  ABC transporter integral membrane type 1
IPR011527  ABC transporter, transmembrane domain, type 1
IPR003439  ABC transporter-like
IPR003593  ATPase, AAA+ type, core

Link to Pubmed  (Pubmed ID)

8889548
8894702
10748049
10819331
11011155
11829140
12477932
13679046
14702039
15302935
15489334
15491607
15518576
15577206
15863492
16344560
16525794
16554024
17977821
18175933
18434309
18952056
19343046
20377823
21194361
21212514
21507922
21906983
22641697
23382691
23974872
24013930

Gene Ontology  (GO ID)

Biological Process

GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0015833  peptide transport
GO:0001916  positive regulation of T cell mediated cytotoxicity
GO:0015031  protein transport
GO:0055085  transmembrane transport

Cellular Component

GO:0005769  early endosome
GO:0005783  endoplasmic reticulum
GO:0030176  integral to endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0005765  lysosomal membrane
GO:0005743  mitochondrial inner membrane
GO:0005886  plasma membrane
GO:0042825  TAP complex

Molecular Function

GO:0005524  ATP binding
GO:0042288  MHC class I protein binding
GO:0015421  oligopeptide-transporting ATPase activity
GO:0042605  peptide antigen binding
GO:0015440  peptide-transporting ATPase activity
GO:0042803  protein homodimerization activity
GO:0022891  substrate-specific transmembrane transporter activity
GO:0046978  TAP1 binding
GO:0046979  TAP2 binding
GO:0046980  tapasin binding