chromobox homolog 7

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Synonym

chromobox homolog 7, Chromobox protein homolog 7, CBX7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:53.30 cerebellum:50.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:786.10 retina:118.60 eye:217.40 artery/aorta:- vein:- lymphnode:60.70 peripheral blood:- spleen:18.90 thymus:12.90 bone marrow:59 adipose:40.30 bone:51.20 skin:33.60
GeneChip cerebrum:9.06 cerebellum:9.88 brain stem:8.76 corpus callosum/glia:8.71 pineal gland:- peripheral nerve:8.55 spine:8.55 retina:- eye:- artery/aorta:8.84 vein:8.44 lymphnode:8.69 peripheral blood:- spleen:9.10 thymus:7.97 bone marrow:7.55 adipose:8.10 bone:- skin:7.84
CAGE cerebrum:4.10 cerebellum:- brain stem:3.89 corpus callosum/glia:3.85 pineal gland:3.75 peripheral nerve:- spine:3.45 retina:- eye:- artery/aorta:4.10 vein:3.57 lymphnode:3.35 peripheral blood:- spleen:3.35 thymus:2.41 bone marrow:- adipose:3.39 bone:- skin:-
RNA-seq cerebrum:4.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.37 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.92 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:3.60 prostate:45.10 ovary:37.30 testis:- heart:51.10 muscle:20.10 esophagus:- stomach:21.20 intestine:32.40 colon:25.40     liver/hepato:10.60        lung:19.60    bladder:125.60 kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:9.30 salivary:-
GeneChip uterus:8.45 placenta:7.18 prostate:8.80 ovary:8.71 testis:7.24 heart:8.40 muscle:8.28 esophagus:7.97 stomach:8.47 intestine:8.04 colon:8.28 liver/hepato:7.54 lung:8.45 bladder:- kidney:8.50 pituitary:8.66 thyroid/parathyroid:8.93 adrenal gland:8.32 pancreas:7.51 breast:8.63 salivary:8.45
CAGE uterus:3.98 placenta:2.66 prostate:4.18 ovary:3.62 testis:3.07 heart:3.65 muscle:3.79 esophagus:3.64 stomach:- intestine:3.28 colon:3.82     liver/hepato:2.58    lung:3.49 bladder:4.04 kidney:3.04 pituitary:3.32 thyroid/parathyroid:3.57 adrenal gland:- pancreas:3.40 breast:3.06 salivary:3.40
RNA-seq uterus:- placenta:- prostate:5.68 ovary:4.54 testis:3.82 heart:3.99 muscle:4.47 esophagus:- stomach:- intestine:- colon:5.00     liver/hepato:2.62        lung:4.24    bladder:- kidney:3.55 pituitary:- thyroid/parathyroid:4.56 adrenal gland:4.37 pancreas:- breast:3.63 salivary:-

Gene Information

IDs

Refseq ID NM_175709
Gene ID 23492
Unigene ID Hs.356416
Probe set ID 212914_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100307
GTEx ID ENSG00000100307

Orthologous Gene

Mouse[1]  NM_144811
Rat[1]  NM_199117

Chromosomal Region

22q13.1  [39,516,172  -  39,548,679]

Gene Family (Interpro ID)

IPR000953  Chromo domain
IPR017984  Chromo domain subgroup

Link to Pubmed  (Pubmed ID)

10369680
10591208
12477932
14647293
15489334
15897876
16537902
17374722
18686603
18701502
18984978
19636380
19706751
20541999
20542683
20723236
21047797
21060834
21282530
21988832
22041561
22214847
22226354
23955597
24250222
24375438
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0000792  heterochromatin
GO:0000790  nuclear chromatin
GO:0005634  nucleus
GO:0031519  PcG protein complex
GO:0035102  PRC1 complex

Molecular Function

GO:0003682  chromatin binding
GO:0035064  methylated histone residue binding
GO:0005515  protein binding
GO:0003727  single-stranded RNA binding