microtubule-actin crosslinking factor 1

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Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:209.80 cerebellum:163.70 brain stem:- corpus callosum/glia:29.20 pineal gland:148.30 peripheral nerve:214.70 spine:336.90 retina:593.20 eye:270.30 artery/aorta:119.90 vein:66.60 lymphnode:222.40 peripheral blood:91.10 spleen:94.50 thymus:90.20 bone marrow:236.20 adipose:242 bone:64 skin:340.80
GeneChip cerebrum:8.22 cerebellum:8 brain stem:8.30 corpus callosum/glia:8.68 pineal gland:- peripheral nerve:7.22 spine:8.75 retina:- eye:- artery/aorta:8.19 vein:8.55 lymphnode:7.73 peripheral blood:- spleen:8.23 thymus:7.82 bone marrow:6.61 adipose:7.85 bone:- skin:7.93
CAGE cerebrum:4.51 cerebellum:- brain stem:4.64 corpus callosum/glia:4.60 pineal gland:4.80 peripheral nerve:- spine:4.82 retina:- eye:- artery/aorta:4.84 vein:4.17 lymphnode:4.17 peripheral blood:- spleen:4.34 thymus:3.97 bone marrow:- adipose:4.17 bone:- skin:-
RNA-seq cerebrum:4.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.77 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.51 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:227.80 placenta:225.90 prostate:191.50 ovary:298.10 testis:138.40 heart:153.30 muscle:40.20 esophagus:- stomach:339.90 intestine:64.80 colon:474.90     liver/hepato:137.20        lung:283.50    bladder:- kidney:93.60 pituitary:232 thyroid/parathyroid:163.70 adrenal gland:253.90 pancreas:284.50 breast:473.90 salivary:328.40
GeneChip uterus:8.60 placenta:7.88 prostate:7.91 ovary:8.43 testis:7.33 heart:8.04 muscle:6.97 esophagus:7.27 stomach:7.75 intestine:7.47 colon:6.85 liver/hepato:7.54 lung:9.51 bladder:- kidney:7.50 pituitary:7.68 thyroid/parathyroid:8.13 adrenal gland:7.82 pancreas:6.15 breast:8 salivary:7.49
CAGE uterus:5.03 placenta:4.06 prostate:4.27 ovary:4.56 testis:3.65 heart:4.52 muscle:3.95 esophagus:4.18 stomach:- intestine:3.89 colon:4.19     liver/hepato:3.32    lung:4.39 bladder:4.46 kidney:3.64 pituitary:4.50 thyroid/parathyroid:3.94 adrenal gland:- pancreas:3.13 breast:4.01 salivary:4.27
RNA-seq uterus:- placenta:- prostate:3.68 ovary:4.18 testis:3.67 heart:3.87 muscle:2.18 esophagus:- stomach:- intestine:- colon:3.44     liver/hepato:2.38        lung:5.30    bladder:- kidney:3.55 pituitary:- thyroid/parathyroid:4.04 adrenal gland:3.91 pancreas:- breast:3.61 salivary:-

Gene Information

IDs

Refseq ID NM_012090
Gene ID 23499
Unigene ID Hs.580782
Probe set ID 207358_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000127603
GTEx ID ENSG00000127603

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

1p34.3  [39,546,988  -  39,952,789]

Gene Family (Interpro ID)

IPR002048  Calcium-binding EF-hand
IPR016146  Calponin-homology
IPR001715  Calponin-like actin-binding
IPR018249  EF-HAND 2
IPR018159  Spectrin/alpha-actinin

Link to Pubmed  (Pubmed ID)

1074709
7635207
9455484
10529403
10559237
10574462
10601340
10747097
11112700
11443112
11845288
12168954
12421765
12477932
14636561
14702039
15231748
15265687
15604093
16076900
16097034
16344560
16710414
16815997
17043677
17081983
17113391
18239623
18685082
19405953
19738201
19913121
20237496
20379614
20628086
20686565
20811636
20936779
20937854
21139048
21145461
21295697
21890473
22505724
22586326
22863883
22939629
23000965
23184944
23667531
24163370
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0008150  biological_process
GO:0007050  cell cycle arrest
GO:0006928  cellular component movement
GO:0007163  establishment or maintenance of cell polarity
GO:0043001  Golgi to plasma membrane protein transport
GO:0001707  mesoderm formation
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0006620  posttranslational protein targeting to membrane
GO:0010632  regulation of epithelial cell migration
GO:0051893  regulation of focal adhesion formation
GO:0032886  regulation of microtubule-based process
GO:0016055  Wnt receptor signaling pathway
GO:0042060  wound healing

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005794  Golgi apparatus
GO:0005874  microtubule
GO:0005886  plasma membrane
GO:0032587  ruffle membrane

Molecular Function

GO:0003779  actin binding
GO:0051015  actin filament binding
GO:0016887  ATPase activity
GO:0005509  calcium ion binding
GO:0008017  microtubule binding
GO:0005515  protein binding