nucleoporin 62kDa

 jump to detail

Synonym

nucleoporin 62kDa, FLJ43869, DKFZp547L134, Nuclear pore glycoprotein p62, FLJ20822, MGC841, NUP62, nucleoporin 62kD, 62 kDa nucleoporin

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:156.40 cerebellum:226.70 brain stem:- corpus callosum/glia:291.60 pineal gland:- peripheral nerve:92 spine:112.30 retina:355.90 eye:105.80 artery/aorta:89.90 vein:199.90 lymphnode:313.40 peripheral blood:182.20 spleen:548.30 thymus:193.30 bone marrow:39.40 adipose:80.70 bone:179.10 skin:158.40
GeneChip cerebrum:5.07 cerebellum:5.36 brain stem:5.09 corpus callosum/glia:5.29 pineal gland:- peripheral nerve:5.29 spine:5.14 retina:- eye:- artery/aorta:5.08 vein:4.72 lymphnode:5.88 peripheral blood:- spleen:5.90 thymus:6.70 bone marrow:5.74 adipose:5.19 bone:- skin:5.47
CAGE cerebrum:0.45 cerebellum:- brain stem:0.85 corpus callosum/glia:0.73 pineal gland:0.26 peripheral nerve:- spine:0.68 retina:- eye:- artery/aorta:0.34 vein:1.86 lymphnode:1.47 peripheral blood:- spleen:1.41 thymus:3.38 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:1.27 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.15 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.52 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:127.50 prostate:157.70 ovary:260.80 testis:441.30 heart:102.20 muscle:40.20 esophagus:- stomach:127.50 intestine:64.80 colon:203.50     liver/hepato:73.90        lung:117.30    bladder:125.60 kidney:52 pituitary:- thyroid/parathyroid:327.50 adrenal gland:- pancreas:17.80 breast:92.90 salivary:328.40
GeneChip uterus:5.75 placenta:5.34 prostate:5.63 ovary:5.78 testis:7.67 heart:5.16 muscle:5.22 esophagus:5.90 stomach:5.60 intestine:5.55 colon:6 liver/hepato:4.89 lung:5.32 bladder:- kidney:5.06 pituitary:5.55 thyroid/parathyroid:5.20 adrenal gland:5.52 pancreas:4.91 breast:5.54 salivary:5.35
CAGE uterus:0.54 placenta:1.51 prostate:0.53 ovary:1.00 testis:4.25 heart:0.72 muscle:0.33 esophagus:1.04 stomach:- intestine:0.84 colon:1.69     liver/hepato:1.60    lung:0.95 bladder:0.87 kidney:0.82 pituitary:0.26 thyroid/parathyroid:0.41 adrenal gland:- pancreas:0 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:1.67 ovary:2.71 testis:2.18 heart:1.54 muscle:3.07 esophagus:- stomach:- intestine:- colon:1.36     liver/hepato:0.33        lung:2.22    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:1.95 adrenal gland:1.61 pancreas:- breast:2.40 salivary:-

Gene Information

IDs

Refseq ID NM_153718
Gene ID 23636
Unigene ID Hs.574492
Probe set ID 207740_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000213024
GTEx ID ENSG00000213024

Orthologous Gene

Mouse[4]  NM_053074
Rat[4]  NM_053074

Chromosomal Region

19q13.33  [50,410,086  -  50,432,786]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1915414
7744965
8125298
8537436
8589458
8650207
8702753
8707840
8757804
8889548
9102465
9114010
9348540
9367915
9407313
10330396
10356400
10373430
10395558
10601273
10668806
10781837
10799545
11013214
11073998
11076863
11113176
11230166
11238447
11244088
11256614
11266456
11310559
11425870
11553620
11755531
11852044
12163599
12228227
12477932
12894213
14667819
14702039
14718703
14973189
15175862
15489334
15489336
15507209
15522285
15625236
15820316
15953362
16169070
16189514
16314397
16344560
16381901
16434389
16648475
16730000
16786527
17098863
17500061
17960595
18029348
18292223
18809582
18854154
19144712
19615732
19828735
20360068
20622012
21078624
21139048
21145461
21698267
21726808
21890473
21906983
21988832
22110128
22308026
22334672
22505724
22558357
22928108
22939629
23383273
23777819
24074597
24250222
24418548
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0007569  cell aging
GO:0008219  cell death
GO:0007166  cell surface receptor linked signal transduction
GO:0019221  cytokine-mediated signaling pathway
GO:0015758  glucose transport
GO:0008645  hexose transport
GO:0009755  hormone-mediated signaling pathway
GO:0000278  mitotic cell cycle
GO:0007077  mitotic nuclear envelope disassembly
GO:0051028  mRNA transport
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0043407  negative regulation of MAP kinase activity
GO:0043069  negative regulation of programmed cell death
GO:0046580  negative regulation of Ras protein signal transduction
GO:0006913  nucleocytoplasmic transport
GO:0045742  positive regulation of epidermal growth factor receptor signaling pathway
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0015031  protein transport
GO:0010827  regulation of glucose transport
GO:0046578  regulation of Ras protein signal transduction
GO:0009966  regulation of signal transduction
GO:0006351  transcription, DNA-dependent
GO:0055085  transmembrane transport
GO:0016032  viral reproduction

Cellular Component

GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0005635  nuclear envelope
GO:0031965  nuclear membrane
GO:0005643  nuclear pore
GO:0031074  nucleocytoplasmic shuttling complex
GO:0046930  pore complex
GO:0030529  ribonucleoprotein complex
GO:0000922  spindle pole

Molecular Function

GO:0003682  chromatin binding
GO:0005487  nucleocytoplasmic transporter activity
GO:0005515  protein binding
GO:0051425  PTB domain binding
GO:0030159  receptor signaling complex scaffold activity
GO:0042169  SH2 domain binding
GO:0017056  structural constituent of nuclear pore
GO:0046966  thyroid hormone receptor binding
GO:0043130  ubiquitin binding