plexin B2

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Synonym

KIAA0315, plexin B2, PLEXB2, Nbla00445, Plexin-B2 precursor, MM1, PLXNB2, dJ402G11.3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:152.90 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:355.90 eye:41.10 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:24
GeneChip cerebrum:7.37 cerebellum:8.85 brain stem:7.31 corpus callosum/glia:7.97 pineal gland:- peripheral nerve:8.30 spine:7.94 retina:- eye:- artery/aorta:8.99 vein:8.07 lymphnode:8.75 peripheral blood:- spleen:9.43 thymus:6.96 bone marrow:6.87 adipose:8.43 bone:- skin:8.75
CAGE cerebrum:3.21 cerebellum:- brain stem:2.91 corpus callosum/glia:3.61 pineal gland:2.81 peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:4.40 vein:3.54 lymphnode:3.80 peripheral blood:- spleen:4.22 thymus:2.10 bone marrow:- adipose:3.55 bone:- skin:-
RNA-seq cerebrum:2.53 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.73 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.57 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:33.80 ovary:37.30 testis:17.30 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:34.20    bladder:- kidney:- pituitary:- thyroid/parathyroid:327.50 adrenal gland:- pancreas:168.90 breast:27.90 salivary:-
GeneChip uterus:9.05 placenta:9.05 prostate:9.26 ovary:9.48 testis:8.49 heart:7.80 muscle:6.04 esophagus:9.41 stomach:9.33 intestine:8.13 colon:8.66 liver/hepato:9.12 lung:9.09 bladder:- kidney:9.61 pituitary:8.98 thyroid/parathyroid:9.50 adrenal gland:9 pancreas:7.86 breast:9.29 salivary:8.69
CAGE uterus:4.17 placenta:4.17 prostate:4.27 ovary:4.35 testis:3.94 heart:3.44 muscle:2.47 esophagus:4.21 stomach:- intestine:3.74 colon:3.83     liver/hepato:3.72    lung:4.05 bladder:3.91 kidney:4.26 pituitary:3.73 thyroid/parathyroid:4.64 adrenal gland:- pancreas:3.89 breast:3.43 salivary:4.00
RNA-seq uterus:- placenta:- prostate:4.66 ovary:5.37 testis:3.87 heart:2.61 muscle:1.87 esophagus:- stomach:- intestine:- colon:3.53     liver/hepato:3.92        lung:4.46    bladder:- kidney:4.50 pituitary:- thyroid/parathyroid:5.37 adrenal gland:4.26 pancreas:- breast:4.01 salivary:-

Gene Information

IDs

Refseq ID NM_012401
Gene ID 23654
Unigene ID Hs.398989
Probe set ID 208890_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196576
GTEx ID ENSG00000196576

Orthologous Gene

Mouse[2]  NM_001159521, NM_138749
Rat [0]  

Chromosomal Region

22q13.33  [50,713,408  -  50,746,056]

Gene Family (Interpro ID)

IPR002909  Cell surface receptor IPT/TIG
IPR014756  Immunoglobulin E-set
IPR003659  Plexin/semaphorin/integrin
IPR001627  Semaphorin/CD100 antigen
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

7889532
8593609
9205841
10520995
10591208
12123608
12183458
12477932
12533544
12730235
14702039
15146197
15184888
15489334
16169070
16303743
18029348
19805522
21139048
21890473
21900206
21906983
21963094
21987572
22268729
22939629
23000965
24158112

Gene Ontology  (GO ID)

Biological Process

GO:0007420  brain development
GO:0001843  neural tube closure
GO:0007405  neuroblast proliferation
GO:0050772  positive regulation of axonogenesis
GO:0008360  regulation of cell shape
GO:0001932  regulation of protein amino acid phosphorylation
GO:0032319  regulation of Rho GTPase activity

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005622  intracellular

Molecular Function

GO:0005096  GTPase activator activity
GO:0005515  protein binding
GO:0017154  semaphorin receptor activity