Ral GTPase activating protein, alpha subunit 1 (catalytic)

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Synonym

GRIPE, TULIP1, GTPase activating RANGAP domain-like 1, Tuberin-like protein 1, GTPase-activating Rap/Ran-GAP domain-like 1, DKFZp667F074, DKFZp566D133, KIAA0884, Tulip1, GTPase activating Rap/RanGAP domain-like 1, GARNL1, GAP-related-interacting partner to E12

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.50 cerebellum:88.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:61.30 spine:112.30 retina:- eye:52.90 artery/aorta:30 vein:- lymphnode:40.40 peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:24
GeneChip cerebrum:7.74 cerebellum:7.90 brain stem:7.91 corpus callosum/glia:7.74 pineal gland:- peripheral nerve:7.57 spine:7.59 retina:- eye:- artery/aorta:6.87 vein:6.45 lymphnode:6.87 peripheral blood:- spleen:6.63 thymus:7.05 bone marrow:4.98 adipose:6.47 bone:- skin:6.89
CAGE cerebrum:4.19 cerebellum:- brain stem:4.30 corpus callosum/glia:4.28 pineal gland:4.66 peripheral nerve:- spine:4.06 retina:- eye:- artery/aorta:3.72 vein:3.65 lymphnode:3.47 peripheral blood:- spleen:3.52 thymus:3.66 bone marrow:- adipose:3.81 bone:- skin:-
RNA-seq cerebrum:1.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.62 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:40.10 prostate:11.30 ovary:74.50 testis:43.30 heart:- muscle:40.20 esophagus:- stomach:21.20 intestine:32.40 colon:101.80     liver/hepato:52.80        lung:24.40    bladder:- kidney:93.60 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:62.20 breast:102.20 salivary:-
GeneChip uterus:7.47 placenta:6.13 prostate:7.96 ovary:7.29 testis:6.54 heart:6.53 muscle:6.97 esophagus:6.66 stomach:6.76 intestine:6.55 colon:6.04 liver/hepato:6.39 lung:6.95 bladder:- kidney:6.55 pituitary:7.67 thyroid/parathyroid:7.23 adrenal gland:7.55 pancreas:5.80 breast:6.99 salivary:6.57
CAGE uterus:4.14 placenta:3.23 prostate:3.90 ovary:4.12 testis:3.48 heart:3.56 muscle:3.38 esophagus:3.86 stomach:- intestine:3.75 colon:3.78     liver/hepato:3.01    lung:3.88 bladder:3.84 kidney:3.60 pituitary:4.78 thyroid/parathyroid:3.67 adrenal gland:- pancreas:3.52 breast:3.80 salivary:3.40
RNA-seq uterus:- placenta:- prostate:1.00 ovary:2.23 testis:2.03 heart:0.64 muscle:0.66 esophagus:- stomach:- intestine:- colon:0.96     liver/hepato:0.77        lung:0.89    bladder:- kidney:1.38 pituitary:- thyroid/parathyroid:1.86 adrenal gland:1.51 pancreas:- breast:0.86 salivary:-

Gene Information

IDs

Refseq ID NM_194301
Gene ID 253959
Unigene ID Hs.113150
Probe set ID 213049_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000174373
GTEx ID ENSG00000174373

Orthologous Gene

Mouse[3]  NM_001003719, NM_001112714, NM_019994
Rat[3]  NM_001003719, NM_001112714, NM_019994

Chromosomal Region

14q13.2  [36,007,558  -  36,278,510]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10048485
12200424
12477932
14702039
15037602
15252450
15489334
15498464
16903783
18029348
19520869
19710015
19733229
20379614
20811636
21139048
24255178
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0032859  activation of Ral GTPase activity
GO:0043547  positive regulation of GTPase activity
GO:0006355  regulation of transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0005096  GTPase activator activity
GO:0046982  protein heterodimerization activity
GO:0017123  Ral GTPase activator activity