gamma-aminobutyric acid (GABA) B receptor, 1

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Synonym

GABA-B receptor 1, dJ271M21.1.1, GABBR1-3, GABAB(1e), hGB1a, GABABR1, dJ271M21.1.2, Gb1, GABA-B-R1, GABBR1, GPRC3A, gamma-aminobutyric acid (GABA) B receptor, 1, GABA-B receptor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:580.70 cerebellum:1612 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:673.80 retina:237.30 eye:94 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:36.40 spleen:75.60 thymus:- bone marrow:39.40 adipose:- bone:38.40 skin:115.20
GeneChip cerebrum:9.39 cerebellum:9.51 brain stem:8.83 corpus callosum/glia:8.05 pineal gland:- peripheral nerve:8.06 spine:8.18 retina:- eye:- artery/aorta:7.71 vein:6.92 lymphnode:7.23 peripheral blood:- spleen:7.64 thymus:6.30 bone marrow:7.06 adipose:6.95 bone:- skin:6.82
CAGE cerebrum:5.20 cerebellum:- brain stem:4.39 corpus callosum/glia:4.64 pineal gland:3.16 peripheral nerve:- spine:4.38 retina:- eye:- artery/aorta:3.21 vein:2.67 lymphnode:2.18 peripheral blood:- spleen:2.28 thymus:1.35 bone marrow:- adipose:1.88 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:18.20 prostate:56.30 ovary:74.50 testis:21.60 heart:38.30 muscle:40.20 esophagus:- stomach:42.50 intestine:32.40 colon:8.50     liver/hepato:42.20        lung:53.80    bladder:125.60 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:8.90 breast:158 salivary:-
GeneChip uterus:7.52 placenta:6.19 prostate:7.15 ovary:6.63 testis:6.05 heart:6.78 muscle:6.04 esophagus:6.53 stomach:6.88 intestine:6.26 colon:6.71 liver/hepato:6.16 lung:7.11 bladder:- kidney:6.51 pituitary:7.58 thyroid/parathyroid:6.62 adrenal gland:7.29 pancreas:5.06 breast:6.92 salivary:6.08
CAGE uterus:3.33 placenta:1.08 prostate:3.04 ovary:2.78 testis:1.87 heart:2.69 muscle:1.35 esophagus:2.60 stomach:- intestine:1.89 colon:2.69     liver/hepato:0.55    lung:2.58 bladder:2.88 kidney:1.44 pituitary:3.16 thyroid/parathyroid:2.16 adrenal gland:- pancreas:1.42 breast:2.11 salivary:2.12
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_021903
Gene ID 2550
Unigene ID Hs.167017
Probe set ID 203146_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204681
GTEx ID ENSG00000204681

Orthologous Gene

Mouse[2]  NM_019439
Rat [0]  

Chromosomal Region

HSCHR6_MHC_APD  [29,523,504  -  29,601,074]
HSCHR6_MHC_MANN  [29,522,994  -  29,600,557]
HSCHR6_MHC_MCF  [29,523,204  -  29,600,766]
HSCHR6_MHC_DBB  [29,523,343  -  29,600,923]
HSCHR6_MHC_COX  [29,519,995  -  29,597,568]
6p22.1  [29,523,406  -  29,601,753]
HSCHR6_MHC_QBL  [29,523,310  -  29,600,897]

Gene Family (Interpro ID)

IPR000337  GPCR, family 3
IPR002455  GPCR, family 3, gamma-aminobutyric acid receptor, type B
IPR002456  GPCR, family 3, gamma-aminobutyric acid receptor, type B1
IPR000436  Sushi/SCR/CCP

Link to Pubmed  (Pubmed ID)

2834384
7927650
8125298
9069281
9753614
9798068
9844003
9872316
9872744
9889352
9933300
10075644
10328880
10402495
10587080
10773016
10906333
11087824
11140838
11178869
11844143
12115687
12130687
12477932
12555235
12601092
12645817
12770685
12923192
14574404
14625043
14643764
14707142
14718537
14759258
14961561
14966130
14978362
15174051
15304491
15309313
15474078
15482257
15489334
15660124
15685626
15759131
15799783
15820424
15857448
15863499
15946333
16169070
16176975
16344560
16499773
16724110
16829628
17185339
17264536
17412563
17474147
17591780
17971048
18098271
18255321
18355961
18403780
18653317
19002745
19052921
19086053
19327013
19664746
19763258
19850743
19851445
20036641
20195357
20378664
20379614
20398908
20468064
20538960
20557420
20655478
20655479
20655480
20655481
20655482
20655483
20655490
21124972
21303731
21621395
21932037
22321358
22412388
22613715
22660477
22722631
23007731
23192081
23391219
24778228

Gene Ontology  (GO ID)

Biological Process

GO:0007214  gamma-aminobutyric acid signaling pathway
GO:0007194  negative regulation of adenylate cyclase activity
GO:0007268  synaptic transmission

Cellular Component

GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane

Molecular Function

GO:0004965  GABA-B receptor activity
GO:0005515  protein binding