PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

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Synonym

PAN3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:3.22 cerebellum:- brain stem:3.17 corpus callosum/glia:3.45 pineal gland:3.29 peripheral nerve:- spine:3.19 retina:- eye:- artery/aorta:3.34 vein:3.73 lymphnode:3.62 peripheral blood:- spleen:3.77 thymus:4.04 bone marrow:- adipose:3.57 bone:- skin:-
RNA-seq cerebrum:2.12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.57 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:3.58 placenta:3.41 prostate:3.45 ovary:3.28 testis:3.57 heart:2.85 muscle:2.67 esophagus:3.32 stomach:- intestine:3.26 colon:3.30     liver/hepato:2.42    lung:3.73 bladder:3.31 kidney:2.83 pituitary:3.44 thyroid/parathyroid:3.22 adrenal gland:- pancreas:2.90 breast:3.33 salivary:2.99
RNA-seq uterus:- placenta:- prostate:3.48 ovary:3.33 testis:3.39 heart:1.84 muscle:1.69 esophagus:- stomach:- intestine:- colon:2.65     liver/hepato:1.42        lung:3.31    bladder:- kidney:3.03 pituitary:- thyroid/parathyroid:3.53 adrenal gland:4.06 pancreas:- breast:3.60 salivary:-

Gene Information

IDs

Refseq ID NM_175854
Gene ID 255967
Unigene ID Hs.645015
Probe set ID -
Ensembl ID ENSG00000152520
GTEx ID ENSG00000152520

Orthologous Gene

Mouse[2]  NM_028291
Rat[2]  NM_028291

Chromosomal Region

13q12.2  [28,712,643  -  28,869,475]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain

Link to Pubmed  (Pubmed ID)

12477932
12975309
14583602
14702039
15057823
15489334
17785442
18029348
18056425
19322201
19615732
20309963
21139048
21906983
22505724
23398456
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000290  deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0010467  gene expression
GO:0016071  mRNA metabolic process
GO:0000288  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000184  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000289  nuclear-transcribed mRNA poly(A) tail shortening
GO:0010606  positive regulation of cytoplasmic mRNA processing body assembly
GO:0006605  protein targeting
GO:0016070  RNA metabolic process

Cellular Component

GO:0005813  centrosome
GO:0000932  cytoplasmic mRNA processing body
GO:0005829  cytosol
GO:0031251  PAN complex

Molecular Function

GO:0005524  ATP binding
GO:0046872  metal ion binding
GO:0004535  poly(A)-specific ribonuclease activity
GO:0005515  protein binding
GO:0004672  protein kinase activity