F-box and leucine-rich repeat protein 2

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Synonym

FBXL2, F-box and leucine-rich repeat protein 2, F-box/LRR-repeat protein 2, FBL2, F-box protein FBL2/FBL3, DKFZP564P0622

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:116.10 cerebellum:12.60 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:58.80 artery/aorta:60 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:19.20
GeneChip cerebrum:7.18 cerebellum:6.50 brain stem:7.20 corpus callosum/glia:6.46 pineal gland:- peripheral nerve:7.25 spine:6.60 retina:- eye:- artery/aorta:6.46 vein:6.46 lymphnode:5.56 peripheral blood:- spleen:5.51 thymus:5.33 bone marrow:5.72 adipose:5.88 bone:- skin:5.60
CAGE cerebrum:3.34 cerebellum:- brain stem:2.93 corpus callosum/glia:2.67 pineal gland:3.14 peripheral nerve:- spine:2.95 retina:- eye:- artery/aorta:2.81 vein:1.57 lymphnode:0.79 peripheral blood:- spleen:0.66 thymus:0.64 bone marrow:- adipose:1.69 bone:- skin:-
RNA-seq cerebrum:2.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.77 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.40 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:10.90 prostate:22.50 ovary:- testis:95.20 heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:59.40     liver/hepato:21.10        lung:24.40    bladder:125.60 kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:46.50 salivary:-
GeneChip uterus:6.30 placenta:6.49 prostate:6.04 ovary:6.51 testis:7.03 heart:6.27 muscle:5.94 esophagus:5.18 stomach:5.95 intestine:6.17 colon:6.21 liver/hepato:6.08 lung:5.68 bladder:- kidney:6.48 pituitary:7.09 thyroid/parathyroid:6.78 adrenal gland:6.13 pancreas:5.97 breast:6.05 salivary:5.76
CAGE uterus:2.69 placenta:1.86 prostate:2.32 ovary:2.22 testis:3.04 heart:1.62 muscle:0.55 esophagus:1.66 stomach:- intestine:1.46 colon:1.49     liver/hepato:0.26    lung:2.09 bladder:1.76 kidney:2.35 pituitary:3.84 thyroid/parathyroid:2.84 adrenal gland:- pancreas:1.59 breast:2.19 salivary:1.75
RNA-seq uterus:- placenta:- prostate:1.63 ovary:2.10 testis:2.41 heart:0.42 muscle:0.00 esophagus:- stomach:- intestine:- colon:1.08     liver/hepato:0.04        lung:1.29    bladder:- kidney:1.85 pituitary:- thyroid/parathyroid:2.57 adrenal gland:0.31 pancreas:- breast:0.95 salivary:-

Gene Information

IDs

Refseq ID NM_012157
Gene ID 25827
Unigene ID Hs.475872
Probe set ID 214436_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000153558
GTEx ID ENSG00000153558

Orthologous Gene

Mouse[1]  NM_178624
Rat[1]  NM_178624

Chromosomal Region

3p22.3  [33,318,517  -  33,445,154]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10508920
10531035
10531037
10945468
12477932
14702039
15489334
15893726
16169070
16344560
17463251
17784784
22020328
22323446
22399757
22455980
22939624
23370391
23604317
24035498

Gene Ontology  (GO ID)

Biological Process

GO:0006464  protein modification process
GO:0006513  protein monoubiquitination
GO:0006508  proteolysis
GO:0006511  ubiquitin-dependent protein catabolic process
GO:0019048  virus-host interaction

Cellular Component

GO:0005737  cytoplasm
GO:0016020  membrane

Molecular Function

GO:0005516  calmodulin binding
GO:0005515  protein binding
GO:0004842  ubiquitin-protein ligase activity