REX2, RNA exonuclease 2 homolog (S. cerevisiae)

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Synonym

REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, Oligoribonuclease, mitochondrial precursor, MGC111570, SMFN, DKFZP566E144, REXO2, RFN, SFN, Small fragment nuclease, RNA exonuclease 2 homolog

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.33 cerebellum:7.18 brain stem:7.82 corpus callosum/glia:7.84 pineal gland:- peripheral nerve:8.77 spine:7.91 retina:- eye:- artery/aorta:8.77 vein:9.77 lymphnode:8.50 peripheral blood:- spleen:8.76 thymus:7.91 bone marrow:8.74 adipose:8.66 bone:- skin:8.88
CAGE cerebrum:3.41 cerebellum:- brain stem:3.69 corpus callosum/glia:3.37 pineal gland:3.31 peripheral nerve:- spine:3.89 retina:- eye:- artery/aorta:4.44 vein:3.94 lymphnode:3.57 peripheral blood:- spleen:3.81 thymus:3.07 bone marrow:- adipose:3.97 bone:- skin:-
RNA-seq cerebrum:3.55 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.94 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.44 placenta:9.07 prostate:9.63 ovary:9.27 testis:9.26 heart:9.48 muscle:8.34 esophagus:9.36 stomach:8.72 intestine:8.61 colon:8.55 liver/hepato:8 lung:8.91 bladder:- kidney:9.32 pituitary:8.49 thyroid/parathyroid:8.39 adrenal gland:8.88 pancreas:8.65 breast:8.67 salivary:10.28
CAGE uterus:4.52 placenta:4.61 prostate:4.44 ovary:4.13 testis:4.37 heart:4.89 muscle:4.18 esophagus:4.43 stomach:- intestine:3.35 colon:3.97     liver/hepato:4.07    lung:4.00 bladder:4.45 kidney:4.38 pituitary:4.13 thyroid/parathyroid:3.85 adrenal gland:- pancreas:4.11 breast:4.39 salivary:5.14
RNA-seq uterus:- placenta:- prostate:6.05 ovary:5.69 testis:6.22 heart:5.87 muscle:3.34 esophagus:- stomach:- intestine:- colon:6.10     liver/hepato:4.51        lung:5.28    bladder:- kidney:5.65 pituitary:- thyroid/parathyroid:4.99 adrenal gland:5.54 pancreas:- breast:5.30 salivary:-

Gene Information

IDs

Refseq ID NM_015523
Gene ID 25996
Unigene ID -
Probe set ID 218194_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000076043
GTEx ID ENSG00000076043

Orthologous Gene

Mouse[1]  NM_024233
Rat[1]  NM_001008326

Chromosomal Region

11q23.2  [114,310,108  -  114,321,001]

Gene Family (Interpro ID)

IPR006055  Exonuclease
IPR013520  Exonuclease, RNase T/DNA polymerase III
IPR012337  Polynucleotidyl transferase, ribonuclease H fold

Link to Pubmed  (Pubmed ID)

8125298
10810093
10851236
11076863
11230166
11256614
12477932
14702039
15362935
15489334
15489336
15592455
16381901
18023590
18029348
20877624
21139048
21890473
21906983
21963094
23000965
23741365
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006139  nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
GO:0009117  nucleotide metabolic process

Cellular Component

GO:0005739  mitochondrion
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0008408  3'-5' exonuclease activity
GO:0003676  nucleic acid binding