membrane associated guanylate kinase, WW and PDZ domain containing 3

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Synonym

MAGI-3, dJ730K3.2, RP4-730K3.1, MAGI3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:30.70 spine:- retina:593.20 eye:111.70 artery/aorta:30 vein:- lymphnode:30.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:57.60
GeneChip nodata
CAGE cerebrum:2.32 cerebellum:- brain stem:1.76 corpus callosum/glia:1.29 pineal gland:2.13 peripheral nerve:- spine:2.25 retina:- eye:- artery/aorta:2.12 vein:1.80 lymphnode:2.20 peripheral blood:- spleen:1.97 thymus:1.87 bone marrow:- adipose:1.76 bone:- skin:-
RNA-seq cerebrum:1.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.11 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.15 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:22.50 ovary:37.30 testis:30.30 heart:25.50 muscle:- esophagus:- stomach:63.70 intestine:- colon:67.80     liver/hepato:42.20        lung:24.40    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:176.60 salivary:-
GeneChip nodata
CAGE uterus:2.08 placenta:1.82 prostate:2.08 ovary:2.01 testis:1.25 heart:1.97 muscle:0.91 esophagus:2.82 stomach:- intestine:3.68 colon:3.48     liver/hepato:2.43    lung:4.20 bladder:1.73 kidney:2.45 pituitary:2.19 thyroid/parathyroid:3.23 adrenal gland:- pancreas:2.76 breast:3.02 salivary:2.06
RNA-seq uterus:- placenta:- prostate:0.22 ovary:0.12 testis:0.54 heart:0.05 muscle:0.13 esophagus:- stomach:- intestine:- colon:0.26     liver/hepato:0.00        lung:0.03    bladder:- kidney:0.18 pituitary:- thyroid/parathyroid:0.23 adrenal gland:0.16 pancreas:- breast:0.10 salivary:-

Gene Information

IDs

Refseq ID NM_152900
Gene ID 260425
Unigene ID Hs.486189
Probe set ID -
Ensembl ID ENSG00000081026
GTEx ID ENSG00000081026

Orthologous Gene

Mouse[3]  NM_001159354, NM_133853
Rat[1]  NM_139084, NM_133853

Chromosomal Region

1p13.2  [113,933,371  -  114,228,545]

Gene Family (Interpro ID)

IPR008144  Guanylate kinase
IPR008145  Guanylate kinase/L-type calcium channel
IPR001202  WW/Rsp5/WWP

Link to Pubmed  (Pubmed ID)

10748157
10997877
11969287
12140759
12421765
12477932
12615970
14702039
15195140
15652357
16316992
16904289
16964398
18518978
19071123
19144635
19615732
20379614
21134377
21853274
23251661
23568457
23782696

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0043507  positive regulation of JUN kinase activity
GO:0019048  virus-host interaction

Cellular Component

GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0005923  tight junction

Molecular Function

GO:0005524  ATP binding
GO:0005109  frizzled binding
GO:0004385  guanylate kinase activity
GO:0005515  protein binding