WD repeat domain, phosphoinositide interacting 2

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Synonym

FLJ12979, FLJ14217, DKFZP434J154, WIPI2, WIPI-2, WIPI49-like protein 2, CGI-50, DKFZp686P02188, WD repeat domain, phosphoinositide interacting 2, Atg21, FLJ42984

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:105.50 cerebellum:25.20 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:122.70 spine:- retina:- eye:117.50 artery/aorta:- vein:- lymphnode:121.30 peripheral blood:91.10 spleen:75.60 thymus:12.90 bone marrow:78.70 adipose:80.70 bone:64 skin:124.80
GeneChip cerebrum:8.61 cerebellum:8.39 brain stem:8.41 corpus callosum/glia:8.43 pineal gland:- peripheral nerve:8.55 spine:8.33 retina:- eye:- artery/aorta:8.29 vein:8.03 lymphnode:8.29 peripheral blood:- spleen:8.52 thymus:8.31 bone marrow:8.56 adipose:8.32 bone:- skin:8.59
CAGE cerebrum:3.95 cerebellum:- brain stem:3.65 corpus callosum/glia:3.75 pineal gland:3.65 peripheral nerve:- spine:3.71 retina:- eye:- artery/aorta:3.63 vein:3.50 lymphnode:3.44 peripheral blood:- spleen:3.29 thymus:3.49 bone marrow:- adipose:3.32 bone:- skin:-
RNA-seq cerebrum:0.33 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.70 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:127.50 prostate:169 ovary:37.30 testis:177.40 heart:204.30 muscle:20.10 esophagus:- stomach:42.50 intestine:- colon:67.80     liver/hepato:126.70        lung:92.90    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:115.60 breast:111.50 salivary:-
GeneChip uterus:8.26 placenta:8.10 prostate:8.63 ovary:8.40 testis:9.91 heart:8.14 muscle:7.81 esophagus:8.74 stomach:8.28 intestine:7.95 colon:8.09 liver/hepato:8.46 lung:8.37 bladder:- kidney:8.75 pituitary:8.40 thyroid/parathyroid:8.59 adrenal gland:8.28 pancreas:7.87 breast:8.74 salivary:8.60
CAGE uterus:3.39 placenta:3.52 prostate:3.30 ovary:3.02 testis:4.19 heart:3.61 muscle:3.37 esophagus:3.34 stomach:- intestine:3.11 colon:3.36     liver/hepato:3.30    lung:3.56 bladder:3.16 kidney:3.24 pituitary:3.42 thyroid/parathyroid:3.49 adrenal gland:- pancreas:3.65 breast:3.45 salivary:3.56
RNA-seq uterus:- placenta:- prostate:0.99 ovary:0.96 testis:1.30 heart:0.87 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.54     liver/hepato:0.45        lung:0.58    bladder:- kidney:1.81 pituitary:- thyroid/parathyroid:0.49 adrenal gland:1.58 pancreas:- breast:1.04 salivary:-

Gene Information

IDs

Refseq ID NM_015610
Gene ID 26100
Unigene ID Hs.122363
Probe set ID 204710_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000157954
GTEx ID ENSG00000157954

Orthologous Gene

Mouse[2]  NM_178398
Rat[1]  NM_001007615

Chromosomal Region

7p22.1  [5,229,819  -  5,273,457]

Gene Family (Interpro ID)

IPR001680  WD40 repeat

Link to Pubmed  (Pubmed ID)

9847074
10810093
11076863
11230166
11256614
12477932
12853948
14702039
15489334
15489336
15602573
16169070
16381901
18029348
20505359
20562859
21044950
21139048
21145461
21564513
21906983
21963094
22505724
22939629
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0000045  autophagic vacuole formation
GO:0000046  autophagic vacuole fusion

Cellular Component

GO:0005776  autophagic vacuole
GO:0000421  autophagic vacuole membrane
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0034045  pre-autophagosomal structure membrane
GO:0043234  protein complex

Molecular Function

GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0080025  phosphatidylinositol-3,5-bisphosphate binding
GO:0005515  protein binding