growth arrest-specific 1

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Synonym

growth arrest-specific 1, Growth-arrest-specific protein 1 precursor, GAS1, GAS-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:30.70 spine:- retina:- eye:35.30 artery/aorta:119.90 vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:19.70 adipose:40.30 bone:25.60 skin:28.80
GeneChip cerebrum:5.15 cerebellum:4.40 brain stem:4.83 corpus callosum/glia:5.83 pineal gland:- peripheral nerve:6.27 spine:5.42 retina:- eye:- artery/aorta:7.70 vein:8.63 lymphnode:6.06 peripheral blood:- spleen:5.18 thymus:6.20 bone marrow:3.91 adipose:9.01 bone:- skin:8.13
CAGE cerebrum:1.20 cerebellum:- brain stem:1.41 corpus callosum/glia:2.05 pineal gland:1.07 peripheral nerve:- spine:1.11 retina:- eye:- artery/aorta:4.05 vein:3.83 lymphnode:2.24 peripheral blood:- spleen:1.54 thymus:1.96 bone marrow:- adipose:3.22 bone:- skin:-
RNA-seq cerebrum:1.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.89 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.49 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:14.60 prostate:45.10 ovary:37.30 testis:4.30 heart:166 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:19.60    bladder:- kidney:135.20 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:46.50 salivary:-
GeneChip uterus:8.83 placenta:8.22 prostate:8.03 ovary:9.29 testis:5.08 heart:8.36 muscle:6.84 esophagus:7.39 stomach:7.50 intestine:7.13 colon:7.49 liver/hepato:5.21 lung:6.62 bladder:- kidney:7.05 pituitary:5.47 thyroid/parathyroid:7.09 adrenal gland:7.49 pancreas:6.13 breast:9 salivary:6.48
CAGE uterus:4.60 placenta:4.38 prostate:3.87 ovary:4.27 testis:2.68 heart:3.16 muscle:2.82 esophagus:3.16 stomach:- intestine:2.14 colon:3.08     liver/hepato:0.96    lung:2.46 bladder:3.41 kidney:2.30 pituitary:2.08 thyroid/parathyroid:2.63 adrenal gland:- pancreas:2.66 breast:3.52 salivary:1.95
RNA-seq uterus:- placenta:- prostate:5.13 ovary:5.03 testis:3.95 heart:2.74 muscle:2.41 esophagus:- stomach:- intestine:- colon:3.74     liver/hepato:0.91        lung:1.68    bladder:- kidney:3.44 pituitary:- thyroid/parathyroid:3.71 adrenal gland:2.93 pancreas:- breast:4.20 salivary:-

Gene Information

IDs

Refseq ID NM_002048
Gene ID 2619
Unigene ID Hs.65029
Probe set ID 204457_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000180447
GTEx ID ENSG00000180447

Orthologous Gene

Mouse[2]  NM_008086
Rat[2]  NM_008086

Chromosomal Region

9q21.33  [89,559,279  -  89,562,104]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1505026
7956349
8127893
8307588
8889548
9466658
10996315
11356029
11572986
11846389
11906213
12477932
15070677
15103018
16551639
17726382
18394855
18981472
19322201
19460624
19638344
20050020
20301702
20583177
20628624
21111449
21357679
21842183
21890473
21901158
21971401
22311470
22846196
23254899

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0043010  camera-type eye development
GO:0007050  cell cycle arrest
GO:0045165  cell fate commitment
GO:0021587  cerebellum morphogenesis
GO:0048589  developmental growth
GO:0021904  dorsal/ventral neural tube patterning
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0042733  embryonic digit morphogenesis
GO:0048592  eye morphogenesis
GO:0042474  middle ear morphogenesis
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0050680  negative regulation of epithelial cell proliferation
GO:0045930  negative regulation of mitotic cell cycle
GO:0010955  negative regulation of protein maturation by peptide bond cleavage
GO:0045879  negative regulation of smoothened signaling pathway
GO:0042476  odontogenesis
GO:0042473  outer ear morphogenesis
GO:0060021  palate development
GO:0050679  positive regulation of epithelial cell proliferation
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0045880  positive regulation of smoothened signaling pathway
GO:0012501  programmed cell death
GO:0042981  regulation of apoptosis
GO:0060628  regulation of ER to Golgi vesicle-mediated transport
GO:0008589  regulation of smoothened signaling pathway

Cellular Component

GO:0046658  anchored to plasma membrane
GO:0016021  integral to membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding