GATA binding protein 6

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Synonym

Transcription factor GATA-6, GATA6, GATA-binding protein 6, GATA-binding factor 6, GATA binding protein 6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:40.30 bone:- skin:-
GeneChip cerebrum:2.85 cerebellum:2.85 brain stem:2.92 corpus callosum/glia:2.82 pineal gland:- peripheral nerve:2.98 spine:2.88 retina:- eye:- artery/aorta:7.06 vein:6.61 lymphnode:4.41 peripheral blood:- spleen:7.34 thymus:2.76 bone marrow:2.96 adipose:5.19 bone:- skin:3.49
CAGE cerebrum:0.23 cerebellum:- brain stem:0.26 corpus callosum/glia:1.43 pineal gland:1.73 peripheral nerve:- spine:0.87 retina:- eye:- artery/aorta:4.98 vein:3.60 lymphnode:2.37 peripheral blood:- spleen:4.02 thymus:0.50 bone marrow:- adipose:2.48 bone:- skin:-
RNA-seq cerebrum:0.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.12 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:22.50 ovary:223.60 testis:- heart:63.90 muscle:- esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:21.10        lung:63.50    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:17.80 breast:- salivary:-
GeneChip uterus:5.18 placenta:4.76 prostate:3.95 ovary:8.57 testis:5.35 heart:8.20 muscle:3.17 esophagus:3.04 stomach:7.97 intestine:6.63 colon:6.45 liver/hepato:5.45 lung:6.42 bladder:- kidney:3.29 pituitary:2.73 thyroid/parathyroid:4.43 adrenal gland:8.84 pancreas:6.24 breast:4.41 salivary:3.05
CAGE uterus:3.84 placenta:2.74 prostate:4.37 ovary:5.46 testis:3.55 heart:4.81 muscle:1.72 esophagus:2.44 stomach:- intestine:4.84 colon:4.41     liver/hepato:3.72    lung:4.03 bladder:4.54 kidney:2.58 pituitary:1.08 thyroid/parathyroid:2.95 adrenal gland:- pancreas:4.98 breast:3.43 salivary:0.83
RNA-seq uterus:- placenta:- prostate:3.83 ovary:5.24 testis:2.77 heart:3.84 muscle:0.38 esophagus:- stomach:- intestine:- colon:2.24     liver/hepato:2.19        lung:3.19    bladder:- kidney:1.83 pituitary:- thyroid/parathyroid:1.62 adrenal gland:3.19 pancreas:- breast:1.53 salivary:-

Gene Information

IDs

Refseq ID NM_005257
Gene ID 2627
Unigene ID Hs.514746
Probe set ID 210002_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000141448
GTEx ID ENSG00000141448

Orthologous Gene

Mouse[2]  NM_010258
Rat[3]  NM_019185

Chromosomal Region

18q11.2  [19,749,404  -  19,782,491]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
8975704
9294001
9315713
9566909
9593712
10608869
10851229
11375995
11724781
11733512
11889139
12477932
12530677
12530967
12606287
12615657
12679484
12867597
12909592
12944489
12959982
14988427
15016828
15146197
15173203
15388788
15666845
15831526
15913546
16110260
16137232
16150495
16159937
16607277
16968778
17070195
17390031
17403900
17626241
17785913
17848411
18078765
18177748
18227727
18405344
18454176
18535672
18671946
18769116
19497978
19581290
19597127
19628789
19649254
19666519
19760754
19913121
20081228
20581743
20628086
20628624
20631719
20694014
20826533
20864106
21071980
21076612
21127043
21514437
21629665
21811562
21928112
21988832
22158542
22257684
22375031
22407241
22504665
22672670
22750565
22806356
22824924
22962692
23020118
23158662
23175051
23223019
23275439
23313142
23583651
23635550
23707782
23746070
23784465
24089524
24179092

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007596  blood coagulation
GO:0055007  cardiac muscle cell differentiation
GO:0014898  cardiac muscle hypertrophy in response to stress
GO:0060947  cardiac vascular smooth muscle cell differentiation
GO:0071371  cellular response to gonadotropin stimulus
GO:0071456  cellular response to hypoxia
GO:0060486  Clara cell differentiation
GO:0007493  endodermal cell fate determination
GO:0001701  in utero embryonic development
GO:0060575  intestinal epithelial cell differentiation
GO:0001889  liver development
GO:0060430  lung saccule development
GO:0008584  male gonad development
GO:0043066  negative regulation of apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032911  negative regulation of transforming growth factor-beta1 production
GO:0032912  negative regulation of transforming growth factor-beta2 production
GO:0048645  organ formation
GO:0003148  outflow tract septum morphogenesis
GO:0003310  pancreatic A cell differentiation
GO:0003309  pancreatic B cell differentiation
GO:0006644  phospholipid metabolic process
GO:0045766  positive regulation of angiogenesis
GO:0060045  positive regulation of cardiac muscle cell proliferation
GO:0051891  positive regulation of cardioblast differentiation
GO:0071158  positive regulation of cell cycle arrest
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0070848  response to growth factor stimulus
GO:0051145  smooth muscle cell differentiation
GO:0006366  transcription from RNA polymerase II promoter
GO:0035239  tube morphogenesis
GO:0060510  Type II pneumocyte differentiation

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding