glycine amidinotransferase (L-arginine:glycine amidinotransferase)

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Synonym

Transamidinase, GATM, AT, AGAT, L-arginine:glycine amidinotransferase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:241.80 cerebellum:188.90 brain stem:- corpus callosum/glia:379.10 pineal gland:- peripheral nerve:122.70 spine:224.60 retina:- eye:23.50 artery/aorta:30 vein:- lymphnode:10.10 peripheral blood:- spleen:75.60 thymus:- bone marrow:- adipose:121 bone:25.60 skin:24
GeneChip cerebrum:7.64 cerebellum:6.95 brain stem:7.67 corpus callosum/glia:8.70 pineal gland:- peripheral nerve:8.62 spine:9.15 retina:- eye:- artery/aorta:5.20 vein:5.44 lymphnode:5.33 peripheral blood:- spleen:5.23 thymus:4.67 bone marrow:3.63 adipose:4.70 bone:- skin:6.08
CAGE cerebrum:5.08 cerebellum:- brain stem:5.33 corpus callosum/glia:5.78 pineal gland:3.15 peripheral nerve:- spine:5.68 retina:- eye:- artery/aorta:3.54 vein:3.14 lymphnode:3.36 peripheral blood:- spleen:3.77 thymus:2.58 bone marrow:- adipose:2.86 bone:- skin:-
RNA-seq cerebrum:6.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.88 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.71 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:94.70 prostate:11.30 ovary:37.30 testis:147.10 heart:25.50 muscle:80.40 esophagus:- stomach:21.20 intestine:97.20 colon:-     liver/hepato:358.90        lung:68.40    bladder:1381.70 kidney:2131.40 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:373.40 breast:9.30 salivary:-
GeneChip uterus:4.35 placenta:5.75 prostate:5.32 ovary:5.82 testis:7.65 heart:5.42 muscle:6.52 esophagus:5.13 stomach:6.82 intestine:8.44 colon:4.64 liver/hepato:10.31 lung:3.78 bladder:- kidney:10.22 pituitary:5.08 thyroid/parathyroid:6.74 adrenal gland:5.11 pancreas:10.31 breast:5.46 salivary:6.43
CAGE uterus:2.74 placenta:3.52 prostate:3.24 ovary:4.16 testis:4.69 heart:3.25 muscle:3.92 esophagus:3.20 stomach:- intestine:4.86 colon:3.64     liver/hepato:6.69    lung:2.10 bladder:3.55 kidney:5.48 pituitary:2.50 thyroid/parathyroid:3.56 adrenal gland:- pancreas:8.10 breast:3.19 salivary:3.45
RNA-seq uterus:- placenta:- prostate:4.08 ovary:5.14 testis:4.96 heart:2.83 muscle:3.60 esophagus:- stomach:- intestine:- colon:3.67     liver/hepato:7.95        lung:2.43    bladder:- kidney:6.46 pituitary:- thyroid/parathyroid:4.33 adrenal gland:3.54 pancreas:- breast:3.00 salivary:-

Gene Information

IDs

Refseq ID NM_001482
Gene ID 2628
Unigene ID Hs.75335
Probe set ID 203178_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171766
GTEx ID ENSG00000171766

Orthologous Gene

Mouse[1]  NM_025961
Rat[1]  NM_031031

Chromosomal Region

15q21.1  [45,653,322  -  45,670,979]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

3800397
8125298
8313955
9148748
9165070
9218780
9266688
9915841
10893433
11555793
12324495
12468279
12477932
12701824
12709373
14702039
15489334
15978539
16344560
16614068
16769397
16820567
17101918
19430482
20301334
20301745
20360068
20383146
20682460
20877624
21988832
23010440
24004504
24047826

Gene Ontology  (GO ID)

Biological Process

GO:0034641  cellular nitrogen compound metabolic process
GO:0006601  creatine biosynthetic process
GO:0006600  creatine metabolic process
GO:0009790  embryonic development
GO:0046689  response to mercury ion
GO:0007584  response to nutrient
GO:0006979  response to oxidative stress
GO:0043434  response to peptide hormone stimulus
GO:0042246  tissue regeneration

Cellular Component

GO:0005743  mitochondrial inner membrane
GO:0005758  mitochondrial intermembrane space

Molecular Function

GO:0015068  glycine amidinotransferase activity
GO:0016813  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines